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. 2020 Jul 21;34(4):529–539. doi: 10.1007/s40259-020-00432-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Drug retention^a up to 4 years in all patients (a) and those receiving first-line (b) and subsequent-line treatment (c) analyzed by Kaplan–Meier and Hall–Wellner methods to account for the varied follow-up periods of different patients due to the prospective, observational design of the KOBIO registry. Shading indicates 95% Hall–Wellner bands; + indicates censored patients. KOBIO Korean College of Rheumatology Biologics. ^aDefined as time to discontinuation or change of biologic therapy