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Impact of BMP-2 siRNA interference on expression of p-Smad1/5/8: (a) BMP-2 mRNA measured by real-time PCR showed a successful influence of siRNA on the BMP-2 (n = 3); (b) Western blot showed that BMP-2 siRNA could reduce the protein level of p-Smad1/5/8 (n = 3). **p < 0.01.
