Table 1.
Number of Bound Molecules at Early or Late Simulation Times for Small (s1) or Large (s10) Molecules When Scaffolding Sites Were Separated 10 nm (Pbind = 0.9), in Absence or Presence of the Indicated Extra Obstacles at t = 0
| Distance 10 nm | Early (37.5s) | Late (225s) | |
|---|---|---|---|
| s1 | 0 obstacles | 32.90 ± 1.08 | 39.40 ± 0.45 |
| 100 obstacles s1 | 34.00 ± 1.33 (ns) | 39.90 ± 0.85 (ns) | |
| 200 obstacles s1 | 34.50 ± 1.45 (ns) | 39.17 ± 0.48 (ns) | |
| 100 obstacles s10 | 23.00 ± 1.68 (∗∗∗) | 30.60 ± 1.04 (∗∗∗∗) | |
| 200 obstacles s10 | 16.20 ± 0.81 (∗∗∗∗) | 24.80 ± 0.97 (∗∗∗∗) | |
| s10 | 0 obstacles | 28.1 ± 1.34 | 31.3 ± 0.95 |
| 100 obstacles s1 | 22.9 ± 1.48 (∗) | 31.2 ± 0.69 (ns) | |
| 200 obstacles s1 | 15.7 ± 1.00 (∗∗∗∗) | 24.2 ± 0.94 (∗∗∗∗) | |
| 100 obstacles s10 | 8.8 ± 0.98 (∗∗∗∗) | 11.5 ± 0.65 (∗∗∗∗) | |
| 200 obstacles s10 | 2.9 ± 0.43 (∗∗∗∗) | 2.2 ± 0.36 (∗∗∗∗) | |
Obstacles had the same size of the molecule or not. Mean ± SD, t test against 0 obstacles condition, ns: not significant, ∗p < 0.05; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001.