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. 2020 Jun 30;8(7):186. doi: 10.3390/biomedicines8070186

Figure 2.

Figure 2

Expression of IL-6, IL-8, COX-2, and iNOS after Toll-like receptor (TLR)2/4 inhibition in IVD cells. The light grey columns display the control (IVD cells with C. acnes infection but without sparstolonin B treatment), whereas responders are colored in grey and non-responders in black (responders: n = 3, non-responders: n = 2). (a) Gene expression levels of qPCR results (b) Protein expression levels obtained with ELISA. * p < 0.05 relative to control, ** p < 0.01 relative to control, # p < 0.05 between responders and non-responders, ## p < 0.01 between responders and non-responders. Data are shown in mean with SD.