FIG 1.

Magnitudes of breast milk Env-specific IgA and sIgA binding responses by ELISA and functional ADCC antibody titers in transmitting and nontransmitting mothers. The magnitude of breast milk total IgA (A) and sIgA (B) binding to B.con gp140, measured as the area under the curve by ELISA, was higher in transmitting than in nontransmitting women (median log₁₀ AUC, −0.14 versus −0.40 and −0.19 versus −0.37). Breast milk ADCC Ab titer (C) was also higher in transmitting compared to nontransmitting women (median log₁₀ ADCC Ab titer, 1.39 versus 1.31). Medians are represented by horizontal black lines. The box represents the interquartile range, and the dashed lines extend to the highest and lowest values.