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. 2020 Jul 16;10(7):1059. doi: 10.3390/biom10071059

Figure 2.

Figure 2

Hub genes protein-protein interactions (PPI) and enrichment pathways. Using the String database, we analyzed the hub genes present in most significant modules obtained from the Cytoscape plugin Molecular Complex Detection (MCODE) analysis. (A–D) shows the protein–protein interaction network of 30 hub genes present in module A, 23 in module B, 15 in module C, and 60 in module D. (E–H) the enrichment pathway of the hub genes function present in each module. < 1.0e-16 is the p-value for the entire PPI network of each module. The false discovery rate (FDR) is the parameter computed by String for each enrichment pathway for each module.