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. 2020 Jul 10;9(7):1664. doi: 10.3390/cells9071664

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Summary of the cellular sources of HMGB1 and mechanisms of HMGB1-mediated enhancement of tumor cell proliferation. DC = Dendritic cell; IL = Interleukin; MDSC = Myeloid-derived suppressor cell; PD-L1 = Programmed death ligand 1; RAGE = Receptor for advanced glycation end products; TAM = Tumor-associated macrophage; TAN = Tumor-associated neutrophil; TIM-3 = T cell immunoglobulin mucin-3; TLR = Toll-like receptor; Treg = Regulatory T cell; TSLP = Thymic stromal cell lymphopoietin; UVR = Ultraviolet radiation.