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The overview of sphingolipid metabolism. SPT: serine palmitoyltransferase, CerS: ceramide synthase, dhCer desaturase: dihydroceramide desaturase, S1PP: sphingosine-1-phosphate phosphatase, SPHK: sphingosine kinase, SPL: sphingosine-1-phosphate lyase, CDase: ceramidase, SMase: sphingomyelinase, SM synthase: sphingomyelinase synthase, GCS: glucosyl-ceramide synthase.
