Table 3.
Significantly upregulated pathways in the acute infection and slow infection models.
| Group Comparison | Pathway | Statistical Mean 1 | q-Value |
|---|---|---|---|
| CBV3 vs. CBV3-Ctrl | hsa04630 JAK-STAT signaling pathway | 1.33 | 0.2741 |
| Spl-EV vs. Spl-Ctrl | hsa04662 B cell receptor signaling pathway | 1.01 | 0.1844 |
| hsa04660 T cell receptor signaling pathway | 0.96 | 0.1844 | |
| hsa04810 Regulation of actin cytoskeleton | 0.97 | 0.1844 | |
| hsa04722 Neurotrophin signaling pathway | 0.95 | 0.1844 | |
| Spl-Ctrl vs. CBV3-Ctrl | hsa04610 Complement and coagulation cascades | 2.68 | <0.0001 |
| Spl-EV vs. CBV3 | hsa04610 Complement and coagulation cascades | 2.65 | <0.0001 |
1 Quantitative estimate of pathway deregulation.