Figure 2.

The modulatory effect of neoagarotetraose (NT) on the murine gut microbiome. NC: normal control mice. MD: DSS induced colitis mice. NT: DSS induced colitis mice supplemented with NT. (A) Alpha diversity indices impacted by DSS and NT supplementation. *** p < 0.01 based on Wilcoxon Rank Sum testing. (B) Beta diversity based on Principal component analysis (PCA). (C) The relative abundance of select phyla. Absolute log₁₀ Linear Discriminant Analysis (LDA) scores were obtained using the LEfSE algorithm. (D) The relative abundance of the class β Proteobacteria significantly reduced by NT.