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. 2020 Jul 23;5(30):19314. doi: 10.1021/acsomega.0c03190

Correction to “Synthesis and Antimicrobial Activity of Novel Piperidinyl Tetrahydrothieno[2,3-c]isoquinolines and Related Heterocycles”

Remon M Zaki , Adel M Kamal El-Dean, Shaban M Radwan, Asmaa S A Sayed
PMCID: PMC7409241  PMID: 32775936

There were errors in Schemes 1 and 2 in the original manuscript. In Scheme 1, the chemical structure of compound 4 contained the wrong CO group.

Scheme 1. Synthesis of 1-Amino-2-substituted-5-piperidinyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinolines (4a–e).

Scheme 1

In Scheme 2, derivatives 7ac should be corrected as follows:

  • 7b: Ar= C6H4(NO2)-p instead of C6H5(-NO2)-p

  • 7a: Ar= C6H5 instead of C6H5–CHO

  • 7c: Ar= C6H4(OCH3)-p instead of C6H5(OCH3)-p

Also in Scheme 2: the direction of arrow from compound 6 to 7 should be from compounds 5a,b to compound 7.

Scheme 2. Synthesis of the Pyrrolyl Derivatives 5a,b Starting with the Acetyl Derivative 5a To Synthesize Various Chalcones, Pyrazolyl, and Isoxazolyl Compounds 69.

Scheme 2

The corrected schemes are listed below.


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