Table 4.

Inhibition (IC₅₀) of porcine kidney and C. riparius trehalases by compounds 29, 30, 31, 27, 32, 33, 34, nd 35.

Compound	Porcine Kidney, IC50	C. riparius, IC50	Selectivity a
29	>1 mM [93]	177 ± 18 nM [93]	>5649
30	20.6 ± 2.2 μM [93]	1.22 ± 0.08 μM [93]	17
31	>1 mM [93]	175 ± 12 nM [93]	>5714
27	479 ± 45 nM [93]	44 ± 1.0 nM [93]	10
32	190.60 ± 34.14 μM [94]	29.49 ± 7.26 μM [94]	6
33 α,β	7.67 ± 3.91 μM [94]	2.30 ± 0.13 μM [94]	3
33 α	27.64 ± 5.35 μM [94]	9.36 ± 1.49 μM [94]	3
33 β	5.84 ± 0.26 μM [94]	0.784 ± 0.059 μM [94]	7
34 α,β	n.d.	>1 mM	-
35 α,β	n.d.	>1 mM	-

^a Selectivity is the ratio between the IC₅₀ value against porcine kidney trehalase and the IC₅₀ value against C. riparius trehalase; n.d.: not determined.