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. 2020 Jul 16;12(7):765. doi: 10.3390/v12070765

Figure 3.

Figure 3

Exosomes/EVs derived from TBEV infection promote viral dissemination. Exosomes (EXO)/EVs secreted from vertebrate and tick cells infected with TBEV contain viral components to infect the naïve human, vertebrate, or tick cells. Abbreviations: N2a cells, mouse neuroblastoma Neuro-2a; HUVEC, human umbilical vein endothelial cells; HaCaT cells, human skin keratinocytes; bEnd.3 cells, mouse brain-microvascular endothelial cells that constitute the blood-brain barrier.