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. 2020 Jun 2;5(3):e00125-20. doi: 10.1128/mSystems.00125-20

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Copyright © 2020 Männle et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — BiG-SCAPE sequence similarity network (SSN) and nocobactin-like subfamilies visualized in Cytoscape. (A) SSN (c = 0.5) of Nocardia spp. Each node represents one BGC identified by antiSMASH 4.0. Colors represent phylogenetic clades A to F and X. Clade-specific GCFs are highlighted. (B) SSN (c = 0.7) of nocobactin-like BGCs. Representative pathways of different subfamilies (I to IX). Two singletons (X and XI) are shown. Abbreviations: TE, thioesterase; KS, ketosynthase; PKS, polyketide synthase; NRPS, nonribosomal peptide synthetase; NMO, N-monooxygenase; NAT, N-acetyltransferase; NFT, N-formyltransferase; SHMT, serine hydroxymethyltransferase.