Table 1.
Demographics and Characteristics of the First-Time Kidney Transplant Study Population.
| Number of Recipients | |||||
|---|---|---|---|---|---|
| Demographics and Characteristics | All Recipients (n=95) | DSA negative (n=72) | DSA positive (n=23) | P values | |
| Demographics of transplant patients | |||||
| Median Age (average ± standard deviation) | 52.7±12.1 | 53.4±11.8 | 50.8±12.9 | p=0.37 | |
| Female | 39 (41.1%) | 32 (44.4%) | 7 (30.4%) | p=0.23 | |
| African American | 20 (21.1%) | 15 (20.8%) | 5 (21.7%) | p=0.92 | |
| Characteristics of transplant patients | |||||
| Primary cause of renal disease | Diabetes Mellitus | 36 (37.9%) | 29 (40.3%) | 7 (30.4%) | p=0.87 |
| Hypertensive Nephrosclerosis | 12 (12.6%) | 11 (15.3%) | 1 (4.3%) | ||
| Focal Glomerular Sclerosis | 12 (12.6%) | 7 (9.7%) | 5 (21.7%) | ||
| Polycystic Kidneys | 6 (6.3%) | 5 (6.9%) | 1 (4.3%) | ||
| Autoimmune Disease (IgA Nephropathy, Lupus, anti-GBM, Wegener’s) | 12 (12.6%) | 8 (11.1%) | 4 (17.4%) | ||
| Others | 17 (17.9%) | 12 (16.7%) | 5 (21.7%) | ||
| Donor Type | Deceased | 31 (32.6%) | 24 (33.3%) | 7 (30.4%) | p=0.92 |
| Living Related | 18 (18.9%) | 13 (18.1%) | 5 (21.7%) | ||
| Living Unrelated | 46 (48.4%) | 35 (48.6%) | 11 (47.8%) | ||
| Pretransplant Dialysis | 78 (82.1%) | 59 (81.9%) | 19 (82.6%) | p=0.99 | |
| HLA Donor/Recipient Mismatch (avg ± stdev)a | 6.2±2.1 | 6.0±2.1 | 6.8±2.1 | p=0.06 | |
| Pretransplant calculated Panel Reactive Antibody (cPRA)b | |||||
| Number of Recipients with Pretransplant cPRA >0% | 25 (26.3%) | 20 (27.8%) | 5 (21.7%) | p=0.77 | |
a
Donor-recipient HLA mismatches were based on A, B, C, DR, and DQ antigens
b
Pretransplant cPRA for DSA-negative recipients (median cPRA= 47.5%, ranging from 2% to 100%, p=ns) and DSA-positive recipients (median cPRA= 27.8%, ranging from 4% to 94%)