. 2019 Dec 12;10(3):159–167. doi: 10.34172/bi.2020.20

Table 2. Effects of various doses of HESS, GB and GB plus HESS on cardiovascular risk indices in experimental groups .

Groups	Parameters
Groups	non-HDL-C	TC/HDL-C	CVR	AI	LCI	AIP
NC^a	44.90±4.38^b-h	2.07±0.15^b-e	0.85±0.03^b-f	1.07±0.15^b-f	1.39±0.13^b-f	0.18±0.04^b-h
DC^b	202.84±8.81^a,d-h	8.03±0.32^a,d-h	1.80±0.07^a,d-h	7.03±0.32^a,d-h	11.33±0.83^a,d-h	0.50±0.03^a,d-h
HESS-100^c	202.02±8.87^a,c-h	7.91±084^a,d-h	1.77±0.23^a,d-h	6.91±0.84^a,d-h	11.23±1.57^a,d-h	0.49±0.02^a,d-h
HESS-200^d	184.25±12.62^a-c,f-h	6.40±077^a-c,f-h	1.35±0.19^a-c,f-h	5.40±0.77^a-c,f-h	7.53±1.15^a-c,f-h	0.41±0.03^a-c,f-h
HESS-400^e	183.15±15.57^a-c,f-h	6.25±0.83^a-c,f-h	1.28±0.13^a-c,f-h	5.25±0.83^a-c,f-h	7.11±1.26^a-c,f-h	0.39±0.04^a-c,f-h
GB^f	71.13±9.29^a-e	2.77±0.38^b-d	1.04±0.12^b-e	1.77±0.38^b-e	2.75±0.45^a-e	0.29±0.04^a-e
GB+HESS-200^g	63.94±10.07^a-f	2.57±0.37^b-d	0.94±0.15^b-e	1.57±0.37^b-e	2.29±0.47^b-e	0.28±0.04^a-e
GB+HESS-400^h	66.31±11.24^a-e	2.69±0.44^b-d	0.95±0.13^b-e	1.69±0.44^b-e	2.34±0.53^b-e	0.29±0.04^a-e
ANOVA ( P value)	0.001	0.001	0.001	0.001	0.001	0.001

The variables are presented as means ± SD. NC (normal control); DC (diabetic control); HESS (hydroalcoholic extract of S. securidaca seeds); GB (glibenclamide).Groups at the left column have been defined by superscript letters (^a–^h). Superscript letters (^a–^f) within a column denote significant differences ( P < 0.05). CVR (cardiovascular risk): LDL-C/HDL-C; AI (atherogenic index): Non-HDL-C/HDL-C; LCI (Lipoprotein combine index): TC∗TG∗LDL/HDL-C; AIP (Atherogenic index of plasma): log (TG/HDL-C).