Figure 1.

Comparison of the gene expression of 21-month old female sheep in subcutaneous adipose tissue (SAT) relative to visceral adipose tissue (VAT). (A) Volcano plot of differential gene expression by adipose tissue type, comparing the SAT versus VAT from control sheep. Genes are plotted by log-fold change, using “apeglm” for shrinkage, and -log adjusted p-values. Blue points have adjusted p-values < 0.05. Red points also have log-fold change > 2.5. (B) Heatmap of pathways with FDR < 0.05 in the comparison of SAT versus VAT tissue differences. Upregulated gene sets are in blue, downregulated gene sets in red.