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. 2020 May 12;45(10):1689–1697. doi: 10.1038/s41386-020-0704-1

Table 2.

Reduced gray matter volume in patients with GAD.

Brain regions Sphere Cluster size t values MNI Coordinates
L/R (voxels) x y z
GAD < HC
sgACC extending to vmPFC L/R 3392 –6.09 0 12 –6
ITG L 689 –5.21 –48 –60 –18
Insula R 671 –5.21 46.5 0 4.5
dmPFC R 408 –4.39 6 61.5 21

GAD generalized anxiety disorder, HC healthy control, sgACC subgenual anterior cingulate cortex, vmPFC ventromedial prefrontal cortex, ITG inferior temporal gyrus, dmPFC dorsomedial prefrontal cortex, L left hemisphere, R right hemisphere.