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. 2020 Aug 12;15(8):e0236995. doi: 10.1371/journal.pone.0236995

Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended therapy

Harald Baumeister 1,*, Yannik Terhorst 1, Cora Grässle 1, Maren Freudenstein 1, Rüdiger Nübling 2, David Daniel Ebert 3
Editor: Stephan Doering4
PMCID: PMC7423074  PMID: 32785245

Abstract

Blended therapy is a new approach combining advantages of face-to-face psychotherapy and Internet- and mobile-based interventions. Acceptance is a fundamental precondition for its implementation. The aim of this study was to assess 1) the acceptance of psychotherapists towards blended therapy, 2) the effectiveness of an acceptance facilitating intervention (AFI) on psychotherapists’ acceptance towards blended therapy and 3) to identify potential effect moderators. Psychotherapists (N = 284) were randomly assigned to a control (CG) or an intervention group (IG). The IG received a short video showing an example of blended therapy, the CG an attention placebo video. Both groups received a reliable online questionnaire assessing acceptance, effort expectancy, performance expectancy, facilitating conditions, social influence and internet anxiety. Between group differences were examined using t-tests and Mann-Whitney tests. Exploratory analysis was conducted to identify moderators. Psychotherapists in CG showed mixed baseline acceptance towards blended therapy (low = 40%, moderate = 33%, high = 27%). IG showed significantly higher acceptance compared to CG (d = .27, pone-sided = .029; low = 24%, moderate = 47%, high = 30%). Bootstrapped confidence intervals were overlapping. Performance expectancy (d = .35), effort expectancy (d = .44) and facilitating conditions (d = .28) were significantly increased (p < .05). No effects on social influence and internet anxiety were found (p>.05). Exploratory analysis indicated psychodynamic oriented psychotherapists profiting particularly from the AFI. Blended therapy is a promising approach to improve healthcare. Psychotherapists show mixed acceptance, which might be improvable by AFIs, particularly in subpopulations of initially rather skeptical psychotherapists. Forthcoming studies should extend the present study by shifting focus from attitudes to the impact of different forms of AFIs on uptake.

Introduction

Mental disorders are globally highly prevalent and affect people in all regions worldwide [14], accounting for 32.4% of years lived with disability and 13% of disability adjusted life years [5]. Moreover, the pooled relative risk (RR = 2.22, 95%-CI: 2.12–2.33) of mortality among persons with mental disorders is increased by over 120% compared to persons without mental disorders [6].

Several psychotherapeutic and psychopharmacological interventions are effective in the treatment of mental health conditions [7]. However, low perceived need for help and obstructive attitudes towards mental health treatments limit treatment seeking behavior and staying in treatment [8]. Thus, measures to improve peoples´ attitudes towards mental health care are needed to improve peoples´ intention to use mental health services and ultimately make use of the available evidence-based treatment approaches.

This general call for active dissemination of mental health treatments is particularly true for the evidence-based treatment and prevention approach of internet- and mobile-based interventions (IMIs) [9]. IMIs have been shown to be effective and cost-effective across several mental health conditions [1014]. They frequently have been suggested as one option to increase the dissemination of mental health care in light of advantages over conventional face to face therapies such as being time efficient, being spatial and timely independently usable and allowing a higher degree of anonymity for those who perceive psychotherapy as stigmatizing [1518]. On the other hand, IMIs require more self-regulation, self-reflection and self-management competencies, which might lead to time pressure or frustration [19] and might come along with communication problems given the lack of visual cues in the therapeutic process [20].

A newer approach called “blended therapy” integrates the advantages of both IMIs and conventional psychotherapy, aiming to combine the best of two worlds [21]. Blended therapy might save clinicians´ time compared to traditional psychotherapy, increase the effectiveness of current state-of the art treatment, or might on the other side lead to lower dropout rates in IMIs [21]. As such, blended therapy is suggested as a promising innovation for the psychotherapeutic setting [22].

A fundamental precondition to implement blended therapy in routine care would be that both patients and psychotherapists are willing to use blended therapy [2327]. In the field of stand-alone IMIs several studies showed that the baseline acceptance rate of patients towards IMIs is low amongst different clinical target populations [2832]. Informational material (acceptance facilitating interventions [AFIs]) such as short informational videos, aiming to provide trustworthy information, reduce apprehensions and misconceptions, proofed to be capable of improving patients´ acceptance of IMIs [28,29,31,33,34]. Moreover, patients seem to prefer psychotherapist assisted e-mental health services over stand-alone IMIs [25], suggesting blended therapy as a way to go [35]. Still, improving patients´ acceptance and offering blended therapy approaches to patients might not be sufficient, when psychotherapists´ attitudes towards digital supported therapies are not positive. Previous studies focusing on stand-alone IMIs showed advocating attitudes in psychotherapists [3638]. However, only a few studies evaluated attitudes towards blended therapy [27,39]. Schuster and colleagues [27] reported evidence for the general acceptance of blended therapy with no preference of psychotherapists’ attitudes towards web-based or blended therapy compared to face-to-face therapy [27]. Also Becker and Jensen-Doss [39] reported positive average attitudes towards blended therapy. Psychotherapists are important gate keepers of patients’ treatment choice [40]. Hence, increasing the acceptance of psychotherapists towards blended therapy is of utmost importance. Given their effectiveness in patients AFIs might facilitate psychotherapists´ acceptance of digital supported therapies [2729,31,33,34]. Currently, there is no randomized controlled trail evaluating the effectiveness of an AFI on the acceptance of psychotherapists’ towards blend therapy.

Hence, the present studies aimed (1) to investigate the degree of psychotherapists’ acceptance towards blended therapy and (2) to examine the effectiveness of an AFI on psychotherapists’ acceptance towards blended therapy. In the context of psychotherapists’ attitudes towards stand-alone IMIs theoretical orientation (e.g. cognitive behavioral or psychodynamic) is argued to influence the acceptance [3638]. Thus, the effect of an AFI might be moderated by the theoretical orientation. To further examine this thesis as well as to identify other potential moderators (3) exploratory analyses were conducted.

Materials and methods

This study was an experimental study with a balanced (1:1) randomization scheme. In cooperation with five German psychotherapy chambers (Landespsychotherapeutenkammern Baden-Württemberg, Schleswig-Holstein, Bayern, Hessen, Hamburg) and one medical association (Landesärztekammer Hessen) psychotherapists were recruited from November 2016 till February 2017 via e-mail, internet websites and postal mail. Data were collected via unipark (https://www.unipark.com/ [last accessed on 18.02.2020]) and unipark’s randomization feature was used to allocate survey participants randomly to either the intervention group (IG) or control group (CG). To be included in the study, persons had to be a licensed psychotherapist or a psychotherapist in training. The IG received an AFI video and the CG received a placebo video. Detailed information on the intervention and control video are provided the section “experimental conditions” below. The study design was presented to the ethics committee of Ulm University which deemed this study as ethically uncritical.

About 13,740 psychotherapists were contacted primarily via the email distribution lists of the aforementioned psychotherapy chambers. Moreover, the study was advertised via chambers´ homepages. A total of 513 psychotherapists visited the online survey, 284 started the survey, and 233 were included in per-protocol analyses. A post-hoc power analysis (one-sided Wilcoxon–Mann–Whitney test for independent groups) revealed a power of 1-ß = .64 to detect the present effect of d = 0.27 on the acceptance score between IG and CG at an α-level of 5%.

Experimental conditions

Intervention group—Acceptance facilitating intervention (AFI): The AFI was a 5-minute video presenting information about blended therapy. The video discusses potential psychotherapists’ worries about the use of IMIs [41] and facets of the Unified Theory of Acceptance and Use of Technology (UTAUT) [42] to influence the attitude towards blended therapy positively. In this way, dysfunctional beliefs and worries were challenged and advantages of blended therapy was emphasized. The video was framed by scenes from a F2F-psychotherapy session, showing a role-play scene between a psychotherapist and a patient, with actors acting the parts. The video showed an exemplarily integration of internet-based interventions into psychotherapy. After a short psychotherapy scene, an expert in IMIs (HB) presented various ways in which IMIs could be integrated in psychotherapy. For example, exercises of an internet-based intervention between F2F-sessions or the use of internet-interventions for comorbid disorders were shown. This was accompanied by further information about patients’ empowerment, increased self-efficacy and autonomy, efficient use of F2F-sessions, and improvement of healthcare. To further illustrate benefits of blended therapy as well as to reduce worries, an example patient reported about her positive experience with blended therapy (e.g. experienced flexibility, additional support, simplicity and usability of internet-interventions or data security). The video was developed in cooperation with the School of Advanced Professional Studies, University Ulm and elements of a real internet-intervention against panic attacks (https://www.geton-training.de/Panik.php) were used for illustrative purposes. For further information about the AFI the video script (German) is presented in the supporting information.

Control group—Attention placebo video: The attention placebo video was a video of four minutes with a psychotherapist talking about work load and work burden of psychotherapists. Thus, the video was relevant for psychotherapists, however, without an expected specific impact on psychotherapists attitude towards blended therapy. The placebo video is available under: http://www.kbv.de/html/22421.php [last accessed on 18.02.2020].

Measures

Primary outcome

Acceptance was operationalized based on the Unified Theory of Acceptance and Use of Technology (UTAUT) [42], which emerged from eight different acceptance models: Theory of Reasoned Action (TRA; [43]), Technology Acceptance Model (TAM, [44]), Motivational Model (MM; [45]), Theory of Planned Behavior (TPB; [46]), Combined TAM and TPB (C-TAM-TPB; [47]), Model of PC Utilization (MPCU; [48]), Innovation Diffusion Theory (IDT; [49] and Social Cognitive Theory (SCT; [50]). While the model was initially developed and validated in the work context [42], the questionnaire has been successfully transferred to the medical field in prior studies (eg. [28,29,31]). As in the original questionnaire, all items were rated on 5-point scales with response options ranging from “does not apply at all (1)” to “applies completely (5)”. Four items assessed acceptance: 1. Generally, I would consider to test blended therapy, 2. I would use blended therapy regularly, if I had the possibility, 3. I would recommend blended therapy to colleagues and 4. I would NOT use blended therapy (inverted item). Items are summed for a total acceptance score (range: 5–20, mean = 12.5). For the original items of the UTAUT questionnaire see [42]. Reliability was excellent (ωtotal = .94). Furthermore, the construct validity of the adopted UTAUT questionnaire was confirmed in a validation study: Confirmatory factor analysis and structural equation modelling for the proposed UTAUT model yielded an excellent fit [51]. Acceptance was assessed after participants watched the intervention (IG) or attention placebo video (CG).

Secondary outcomes

Based on UTAUT four key predictors (performance expectancy, effort expectancy, social influence, facilitating conditions) were operationalized. Items were based on the UTAUT model [42]. Similar, to the acceptance items, the original UTAUT items were adopted to the medical setting. In addition, internet anxiety was added as a dimension based on previous studies (eg. [28,29,31]). Furthermore, inverted items were created and added in this study to reduce biasing effects caused by the assessment methodology. As outline above the model fit of the adopted UTAUT questionnaire and model (including internet anxiety) is excellent [51].

Performance expectancy was measured by 8 items (reliability, ωtotal = .93), effort expectancy by 6 items (ωtotal = .86), social influence by 3 items (ωtotal = .76), facilitating conditions by 7 items (ωtotal = .80), and Internet anxiety by 3 items (ωtotal = .83). (see Table 1 for items). Items are summed for a total score for each predictor. All five predictor scales were assessed after participants watched the intervention (IG) or attention placebo video (CG).

Table 1. Questionnaire items for secondary outcomes.
Performance expectancy (8 items):
    1. Blended therapy would improve the effectiveness of my treatments.
    2. Blended therapy could support my work and increase my productivity.
    3. Blended therapy would help my patients generally.
    4. I expect blended therapy would hinder the therapeutic relationship1.
    5. Patients’ needs cannot be sufficiently targeted by blended therapy1.
    6. My possibilities to react in certain situations are restricted in blended therapy1.
    7. Blended therapy will not be beneficial for my work, because its development is not practice orientated1.
    8. I cannot imagine to use blended therapy, because of its danger for the therapeutic work1.
Effort expectancy (6 items):
    1. Use of blended therapy would be simple.
    2. I could handle blended therapy easily.
    3. Use of blended therapy would be easy and comprehensible.
    4. Creating patients’ compliance would be difficult1.
    5. Use of blended therapy would create a higher workload for myself1.
    6. It would be hard to integrate blended therapy in my work1.
Social influence (3 items):
    1. My colleagues would advise me to use blended therapy.
    2. My supervisor or experienced colleagues would advise me to use blended therapy.
    3. My colleagues would discourage me from using blended therapy1.
Facilitating conditions (7 items):
    1. I would get support, if I encounter technical problems.
    2. I fulfill all technical requirements to use blended therapy.
    3. Blended therapy can cause problems with data and privacy security1.
    4. I expect additional costs, if I use blended therapy.
    5. I expect additional costs for my patients, if I use blended therapy1 (inverted item).
    6. Handling of blended therapy would be difficult for my patients1.
    7. My patients do not fulfill the technical requirements to use blended therapy1.
Internet anxiety (3 items):
    1. The internet has something threatening to me.
    2. I am afraid making an irrevocable mistake while using the internet.
    3. I am very concerned, when I use the internet.

1 Inverted item

Sociodemographic data and other variables

In addition to age and sex, type of psychotherapy license (psychological psychotherapist, child and adolescents psychotherapist, psychiatrist, psychosomatic practitioner, child and adolescents practitioner, other), therapeutic background (behavior psychotherapy, depth psychotherapy, psychodynamic psychotherapy, other), work setting (practice, counseling center, outpatient clinic, inpatient clinic, other), employment (fulltime, part-time, unemployed, other), technology access at work and home (yes/no), frequency of technology use at work and home (5-point scale), expertise using PCs or internet (5-point scales), prior knowledge of blended therapy (5-point scale), experience with blended therapy (5-point scale) were assessed.

Data analysis

All outcomes were analyzed on a per-protocol basis (PP). Individuals were included in per-protocol analyses (= IG/CG watched the video), if the automated system check, whether the video was played completely, and the self-report check “I watched the video” were positive.

For descriptive purposes, the acceptance scale was split in three categories. Cut-off values were defined by the authors as: low acceptance (acceptance sum score: 5–9), medium acceptance (sum score 10–15) and high acceptance (sum score 15–20). Percentages were calculated for each category in total and for both groups. Differences in the frequencies were assessed by Chi-square test.

To assess whether acceptance of intervention group differs significantly from the control group’s mean acceptance, one-sided t-test was used for mean differences with alpha level set to 5%. The acceptance score in the IG was compared against the acceptance score of the CG. Acceptance was asses after participants watched the intervention and control video, respectively. In presence of non-normally distributed data Mann-Whitney test and bootstrapping were used. The bootstrapped 2.5% and 97.5% quantile of the distribution of the resampled group means were used to identify a group difference. If the groups’ quantiles were overlapping no differences were assumed. The normal distribution assumption was tested via Shapiro-Wilk test. Similar to acceptance Mann-Whitney test and bootstrap was used for secondary outcomes (performance expectancy, effort expectancy, social influence, internet anxiety and facilitating conditions), if scales were not normally distributed. Two-sided tests were used for all secondary outcomes.

A linear regression model was used as explorative analysis to identify moderators on the effect of AFI. The variables age, gender, therapeutic background (behavioral psychotherapy, depth psychotherapy, psychodynamic psychotherapy, other), type of license (psychological psychotherapist, child and adolescents psychotherapist, other) and their interactions with group were inserted in an initial model (all variables were effect coded or z-standardized). Group was dummy-coded (1 = IG). The initial model included a total of 20 predictors, inclusive the intercept and all interactions. In a stepwise procedure non-significant predictors were removed from the model until a final model was achieved. Ordinary Least Square (OLS) estimator was employed.

Missingness

A total of 31 items were used to measure acceptance, effort expectancy, performance expectancy, internet anxiety, social influence and facilitating conditions. Missingness for acceptance score was 2.2%. For effort expectancy, performance expectancy, internet anxiety and facilitating conditions missingness was 4.7%, respectively. Dropout is assumed to be independent of the included variables and missing values. A missing completely at random mechanism (MCAR) [52] was assumed for all six variables. Analyses based on the original data using list-wise exclusion yield similar results as analyses using multiple imputations based on predictive mean matching (m = 20). Since no differences occurred, only results from analyses based on the original data using list-wise exclusion are reported in the present study.

Results

Of 284 participants 140 were randomly assigned to the intervention group and 144 to the control group. Mean age was 48.6 (SD = 11.7) and 59% of all participants were female. Based on the system check 21.4% of the participants of the intervention group and 7.8% in the control group did not watch the video completely. Accordingly, for the per protocol analyses 107 participants remain as IG and 126 as CG (see Fig 1). Further demographics of the analyzed sample are summarized in Table 2.

Fig 1. Flow-chart according to the consort statement.

Fig 1

Table 2. Demographics.

Control group (n = 126) Intervention group (n = 107)
M (SD) | % n M (SD) | % n
Age 49.1 (12.9) 47.1 (10.8)
Sex
    Male 31.0 39 17.8 19
    Female 52.4 66 71.0 76
    Not indicated 16.6 21 11.2 12
Type of license
    Child & adolescents 26.2 33 20.6 22
    Psychological psychotherapist 63.5 80 68.2 73
    Psychosomatic practitioner 0.01 1 0 0
    Other 3.2 4 8.4 9
Therapeutic background1
    Behavioral therapy 54.0 68 57.0 61
    Psychodynamic therapy 13.5 17 9.3 10
    Depth psychology 28.6 36 28.0 6
    other 14.3 18 14 15
Prior-knowledge about blended therapy
    Extent 1.7 (1.1) 1.7 (1.1)
    Valence 1.6 (1.8) 1.3 (1.8)
Experiences with blended therapy
    Extent 2.3 (1.2) 2.3 (1.3)
    valence 2.6 (1.5) 2.3 (1.7)

1 multiple choice.

Level of acceptance

Acceptance measured in CG was low to moderate (M = 11.4, SD = 4.8; low = 39.8%, moderate = 33.3%, high = 26.8%). Acceptance in IG was moderate to high (M = 12.7, SD = 4.5; low = 23.8%, medium = 46.7%, high = 29.5%) (Fig 2). Chi-square test revealed significant differences in the frequencies of acceptance categories (χ2 (2, N = 228) = 7.18, p = 0.028).

Fig 2. Acceptance of psychotherapists towards blended therapy in relation to the experimental conditions.

Fig 2

Between-group effect on acceptance

Acceptance was not normally distributed (Shapiro-Wilk test: p < .001). One-sided Mann-Whitney test showed significant differences between groups (pone-sided = .026). IG showed higher acceptance (MCG = 11.5 [95%-CI: 10.6–12.3], MIG = 12.7 [95%-CI: 11.9–13.6]). The difference between CG and IG in standard deviations is d = 0.27 (95% CI: .01-.53).

Between-group effects on secondary outcomes

Performance expectancy was not normally distributed (Shapiro-Wilk test: p < .001). Mann-Whitney test showed significant differences in location parameters (p = .011). The effect in standard deviations is d = 0.34 (95%-CI: .08–.60) favoring intervention group. Bootstrap resulted in overlapping quantiles (MCG = 24.0 [95%-CI: 22.6–25.3], MIG = 26.5 [95%-CI: 25.1–27.9]). Effort expectancy was normally distributed (Shapiro-Wilk test: p = .166). A t-test revealed significant higher values for IG (MCG = 17.9, MIG = 20.2, t(219.93) = -3.51, p < .001). The effect in standard deviations is d = 0.46 (95%-CI: .20–.71) favoring the IG. Facilitating conditions were normally distributed (Shapiro-Wilk test: p = .130). T-test was significant (t(216,58) = -2.00, p = .046). The mean of IG was MIG = 23.2 and the mean of CG MCG = 22.0 and the effect in standard deviations was d = 0.27 (95%-CI: .01–.53) favoring intervention group. Social influence was not normally distributed (Shapiro-Wilk test: p < .001). Mann-Whitney test showed no significant differences in location parameters (p = .301) and quantiles of bootstrapped means were overlapping (MCG = 7.4 [95%-CI: 7.0–7.9], MIG = 7.87 [95%-CI: 7.41 – 8.34]). Internet anxiety was not normally distributed (Shapiro-Wilk test: p < .001). Mann-Whitney test showed no significant differences in location parameters (p = .759) and quantiles of bootstrapped means were overlapping (MCG = 5.5 [95%-CI: 5.1–6.0], MIG = 5.3 [95%-CI: 4.9–5.8]). Effects on secondary outcomes are summarized in Table 3.

Table 3. Effects on secondary outcomes.

p-value Effect size
Performance expectancy .0111 0.34 (95 %-CI: .08 - .60)
Effort expectancy < .0012 0.46 (95 %-CI: .20 - .71)
Facilitating conditions .0462 0.27 (95 %-CI: .01 - .53)
Social influence .3011 -
Internet anxiety .7591 -

1 based on Mann-Whitney test

2 based on t-test.

Exploratory analysis of effect moderating variables

Results of the exploratory analysis are summarized in Table 4.

Table 4. Exploratory regression results for z-standardized acceptance scores.

Predictors Estimate in SD 95%-CI2
Main effects1
    Intercept -0.09 -0.28 to 0.09
    Group .28 0.07 to 0.49
    Therapeutic background
        Depth psychology -0.37 -0.52 to -0.21
        Psychodynamic -0.07 -0.31 to 0.17
Interaction effects1
    Psychodynamic X Group 0.26 0.04 to 0.47

Adjusted R2 = .18, F(5,193) = 11.63, p < .001.

1 Only significant main and interaction effects are listed. All other predictors were eliminated based on non-significance during the step-wise process.

2 Confidence intervals are based on bootstrap (100,000 draws).

Psychotherapists using depth psychology and other approaches showed less acceptance towards blended therapy compared to psychotherapists with other type of therapeutic background (see Table 1). Individuals within the IG had an increased acceptance by 0.28 standard deviations compared to average. This effect was increased by 0.26 standard deviations for psychodynamic psychotherapists (see Table 1 and Fig 3).

Fig 3. Interaction effect between effect coded group and effect coded psychodynamic therapist.

Fig 3

Discussion

This is the first study examining the effectiveness of an acceptance facilitating intervention [AFI] on the acceptance of psychotherapists towards blended therapy. The effect on the primary outcome acceptance was small to medium (d = 0.27). Further small to medium effects on performance expectancy, effort expectancy and on facilitating conditions were found, but no effects were observed on social influence and internet anxiety. Overall, most psychotherapists showed a moderate to high acceptance in the CG, with an average acceptance substantially above the scale mean. Given the placebo video had no effect on the acceptance, we assume that the acceptance in the CG represents the acceptance in the general psychotherapist population. Explorative analysis revealed that AFI effect on acceptance is almost doubled for psychodynamic psychotherapists. Further, explorative analysis showed that the subpopulation of psychotherapist from a depth psychology background had lower than average acceptance.

Blended therapy is a new approach, which combines advantages of both face-to-face psychotherapy and IMIs [21,26] and seems to be a promising approach to improve the current mental health care situation. Based on the above average baseline acceptance found in this study the fundamental precondition for the implementation of online elements into on-site psychotherapy, namely psychotherapists´ acceptance towards blended therapy, seems to be given, which is in line with previous findings [27]. However, the overall acceptance towards blended therapy should be interpreted carefully, as the present study sample is not representative with only a minimal percentage of the psychotherapists following the study invitation, most probably with a bias towards digitally open psychotherapists. The AFI used in this study showed positive effects on psychotherapists´ acceptance towards blended therapy. This result is in line with other studies examining the effects of AFIs on patients’ acceptance (e.g. [28,29,31]). However, prior studies found higher effect sizes (e.g. d = 0.71 [31]), while showing lower baseline acceptance (e.g. 93.7% of all participants reported a low to moderate acceptance [31]). Based on these differences, one could assume that AFIs are especially effective in populations with low acceptance. The present study design is not able to test this assumption, since a pre-test in the intervention group would have been necessary to estimate an interaction between baseline acceptance and AFI. However, such a design adaptation should be considered carefully, as a pre-post-test design might not be adequate for examining an ultra-short AFI delivered in under 5 minutes [28,29,31]. Furthermore, it has to be highlighted that the present study was not powered to identify a small to medium effect size of d 0.27. Thus, future studies with confirmatory design should replicate the present findings.

Another aim of the study was to identify potential effect moderators. The explorative analysis revealed a subpopulation, which showed lower than average acceptance (psychotherapist using depth psychology). Further, being a psychodynamic psychotherapist was found to be a meaningful moderator, with psychodynamic psychotherapists profiting to a greater extend from the AFI compared to psychotherapists with another background. This finding suggests that short informational videos might be particularly useful as a first step for those who are skeptical or uninformed regarding blended therapy, whereas short AFIs might not be sufficient to further increase acceptance of psychotherapists who are already to some degree open to this approach.

When interpreting the present findings some limitations need to be taken into account. First, some data within this study was not normally distributed. Typically used parametric methods would have led to biased results. Non-parametric tests and bootstrap were used in the analyses to obtain robust results [5355]. Thus, differences between CG and IG could be detected and further exploratory analysis was feasible with all assumptions met. For the latter the explorative character should be highlighted. No a-priori assumptions about which variables moderate the effect of the AFI were made, except for psychotherapeutic orientation. Moreover, the study was neither designed nor powered to detected moderator effects. In addition, group sizes for main effects in the explorative analyses were highly unequal (e.g. ratio for other approaches was roughly 1:6), which means the present analyses was also highly underpowered to detect main effects (e.g. post-hoc power analysis to detect a main effect of d = 0.3 for other approaches yield a power of 33%). Thus, the generalizability of the exploratory analysis should be interpreted carefully and further studies validating the present findings are needed.

Second, in all analyses missing cases were excluded. This procedure leads to unbiased estimates, if missingness is missing completely at random (MCAR) [52]. Yet, this assumption cannot be statistically verified. In the present study, missingness was rather low (< 5%) and a replication with multiple imputations yielded no different results. Hence, results are expected to be at low risk of bias.

Third, there might be a baseline imbalance between the experimental conditions regarding gender, which could have biased the present findings. As the more important it seems to replicate the present findings in further experimental studies in order to substantiate the present evidence.

Fourth, only 284 from potentially over 13,000 psychotherapists took part in the present survey and only 233 were included in analyses. Moreover, participants were recruited mainly via online ways (e.g. emails or website) and the survey was also online. This may have led to a selective “internet friendly/familiar” sample, which is not representative for all psychotherapists. This could also be an explanation for the rather high level of acceptance compared to prior studies in representative patient samples [28,29,31]. At the same time, this argues for a higher impact of AFIs in the whole target group, given the findings, that AFIs were seemingly more effective in initially more skeptical participants.

Fifth, in this study the UTAUT model [42] was used and the AFI and the scales were developed based on this model, extended by internet anxiety as a predictor. All outcomes were measured reliably according to typical cut-off values for internal consistency [56]. Reliability scores were calculated using McDonald’s Omega, which is argued to be a better estimator than the often used Cronbach’s alpha [57,58]. Although the UTAUT model was used in this study, the UTAUT model itself and the legitimacy of the introduced predictor internet anxiety was not evaluated. Future studies should test whether the UTAUT model and its extension applies for blended therapy.

Finally, a different design including a pre-test (with substantial time between pre- and post-assessment to avoid a retest/recall bias) to test whether AFIs are indeed more effective in low-acceptance population should be applied. Thereby, different AFI designs (e.g. information paper, presentation format, testing of an example online-component, targeting special population characteristics such as therapeutic background) might facilitate acceptance in different ways and should be tested accordingly in order to examine the most efficient way of increasing participants´ acceptance. For optimization purposes a multiphase optimization strategy (MOST) using fractional factorial designs as recommended by Collins and colleagues could be used [59,60].

Conclusion

Currently psychotherapists in Germany show a mixed acceptance towards blended therapy, which will likely be in a similar vein found in other countries that are not yet much familiar with digital approaches for treating mental disorders. The AFI within this study had a significant small to moderate overall effect on psychotherapists´ acceptance. Thus, AFIs might be an easy to distribute way of facilitating psychotherapists´ attitudes towards blended therapy. Given that not all participants watched the video, implementation strategies should be developed which ensure that psychotherapists´ actually do watch the video (e.g. as controlled CME training). Finally, forthcoming studies need to go beyond acceptance as the outcome and examine psychotherapists´ actual use of blended therapies, which might shift the focus from attitudes to practical, legal and monetary aspect of implementing blended therapies in our daily psychotherapeutic work. Aiming at increasing actual use of blended therapy, we also expect that AFIs need to be more complex than a five-minute video, using a longitudinal approach based on interventions ranging from information over initial workshops to continuous training on the job.

Supporting information

S1 File. Video script.

(DOCX)

S2 File. Dataset.

(XLSX)

Data Availability

All relevant data are within the manuscript and its Supporting Information files.

Funding Statement

The authors received no specific funding for this work.

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Decision Letter 0

Stephan Doering

24 Jan 2020

PONE-D-20-00142

Impact of an Acceptance Facilitating Intervention on Psychotherapists’ Acceptance of Blended Psychotherapy

PLOS ONE

Dear Dr. Baumeister,

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PLOS ONE

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Reviewer #1: Yes

Reviewer #2: Partly

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Reviewer #1: Yes

Reviewer #2: No

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Reviewer #1: Yes

Reviewer #2: No

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Reviewer #1: Yes

Reviewer #2: Yes

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: This is an informative paper that addresses an important aspect of psychotherapeutical practice. The authors investigate how an acceptance-facilitating intervention affects psychotherapists' acceptance of blended therapy. Since internet- and mobile-based interventions are becoming an increasingly important element of psychotherapy, this research is highly relevant. The methodology is sound, What is missing is a brief discussion of the current state of research on the topic. The authors claim that their study is the first on acceptance-facilitating interventions regarding psychotherapists' acceptance of blended therapy. However, there are several studies on the attitudes vis-a-vis blended therapy and the acceptance thereof among psychotherapists (e.g. Schuster et al. 2018: https://www.jmir.org/2018/12/e11007/; Mayer et al. 2019: https://mental.jmir.org/2019/11/e14018/). Although the study presented by the authors is methodologically more sophisticated than many of the existing studies, which are mainly survey-based, the authors should mention the existing research on the topic. This helps the reader to better understand the relevance of the paper and it also shows the innovativeness of the study. A few short sentences and two or three sources will suffice.

As a minor point, I would suggest a language check by a native speaker. All in all, the language and style are appropriate, but at some points, the wording is odd or wrong (e.g. "normal distributed" instead of "normally distributed").

Reviewer #2: This is an interesting paper about the integration of technology with the traditional face-to-face way to work in psychotherapy. It could be an initial point to understand this phenomenon. The reduced psychotherapist sample and the absence of a pre-post analysis are the main problems of the research. Additionally there are different parts of the research needed of some explanation to improve the understanding of the paper.

The abstract inform that one of the aims of the study was to identify potential effect moderators. The analysis of moderators is more complex than a regression analysis. The use of this term could be generate confusion. They informed the use of an online questionnaire. It is no clear if is an ad hoc questionnaire or a well know questionnaire with an adequate validity and reliability.

In the introduction paragraph (line 55), they uses the acronym RR with no reference to his meaning.

There is a contradiction between the content of IG video. It is a video showing case (line 108) or a presenting information about blended psychotherapy (line 121)? How is produce the video: with real psychotherapist, actors, etc.? The video is not accessible to the URL provided. Nevertheless, the IG video has a positive orientation and the placebo video a clear negative orientation. Could these aspects affect to the results?

The primary outcome is about “blended psychotherapy”. Is it a term well known by the German psychotherapist?

There are a difference in acceptance baseline between CG and IG groups (line 226-229). A t-test show a significant difference t= 2.131, 231 d.f. p>.025. If there are a difference between groups before the experimental manipulation, the results could be reconsidered.

The authors use the title “effect on acceptance” (line 235) but this term is confused. If there is not a pre-post analysis is not correct to use the term “effect”. This confusion is also present in the “effect on secondary outcomes” paragraph.

There is not specific information about the number of variables introducing in the regression analysis. It is important because the higher the number, the higher the variance explained, but there are a specific ratio between variables and cases.

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Reviewer #1: Yes: Dr. Giovanni Rubeis

Reviewer #2: No

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Decision Letter 1

Stephan Doering

29 Apr 2020

PONE-D-20-00142R1

Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended psychotherapy

PLOS ONE

Dear Dr. Baumeister,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Whiule reviewer 1 was satisfied with the revision of your manuscript, reviewer 3raised a few minor issues. Please adress these in your revision.

We would appreciate receiving your revised manuscript by May 29, 2020. When you are ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter.

To enhance the reproducibility of your results, we recommend that if applicable you deposit your laboratory protocols in protocols.io, where a protocol can be assigned its own identifier (DOI) such that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). This letter should be uploaded as separate file and labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. This file should be uploaded as separate file and labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. This file should be uploaded as separate file and labeled 'Manuscript'.

Please note while forming your response, if your article is accepted, you may have the opportunity to make the peer review history publicly available. The record will include editor decision letters (with reviews) and your responses to reviewer comments. If eligible, we will contact you to opt in or out.

We look forward to receiving your revised manuscript.

Kind regards,

Stephan Doering, M.D.

Academic Editor

PLOS ONE

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: All comments have been addressed

Reviewer #3: (No Response)

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2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #3: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #3: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #3: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: (No Response)

Reviewer #3: Yes

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: All comments have been addressed by the authors. The paper is acceptable for publication in its present form

Reviewer #3: This is an interesting article to read, pointing to the importance of acceptance for blended psychotherapy in the treatment giver rather than receiver. Authors have made an effort to improve the manuscript by carefully considering previous reviewers comments. However, there are some points that I think still needs to be addressed.

1. Measures. The questionnaire used in this article, as well as its origins from UTAUT should be more thoroughly described in the method section. Readers who are unfamiliar with this instrument should be provided with enough information to evaluate the applicability of it. For instance, it would be helpful if you added more details on the original instrument, such as total amount of items and number of factors. Please describe how items (or factors) were chosen from the UTAUT, and in what manner they were adapted from the original version (such as; if items are rephrased completely, or adapted by changing some words in the items, and why inverted items were added). If your version is currently being evaluated for psychometric properties, it would be helpful if you mention this in the manuscript. Further, it is unclear where the items on internet anxiety were derived from; the UTAUT or developed by authors?

Since the result section describes deviance from the scale mean, the scale mean should also be stated here (or in the result section if you are referring to the mean of the study sample).

2. Materials and methods. It should be more clearly stated when data was collected, this will make the result section easier to understand, that results are exploring differences after manipulation, not baseline. (You provided this clearly in your answer to reviewer 2, however it is not as clearly described in the article).

3. Data analysis. Authors describe splitting acceptance in three categories (low/medium/high), for descriptive purposes. Could you clarify how you decided on these cut-offs? Are they based on the distribution of responses? Or theoretically derived? Is there any reason not to analyze difference in distributions on acceptance statistically? I think that a chi-square test would be informative on difference in level of acceptance. (seems to be a typo in the medium range where I suppose the range is above 9 and below 16? line 189)

4. In the result section you start by describing a rather high dropout rate in the intervention group. I think the article would benefit from an analysis on difference in characteristics between those who dropped out and those who were completers. This would give a hint if there is a bias in the study sample, if those who dropped out were mostly men, mostly from a specific therapeutic background and so on.

5. In Table 2 it seems as if there is a difference in distribution of gender between groups, with a higher ratio of women to men in the intervention group as compared to control group. Have you checked if this (or other demographics) is a statistically significant difference in distribution? Thoughts on implications if so? (In my version the tab-spacing made table 2 almost uninterpretable, be sure to double-check this before publication).

6. The concept of blended psychotherapy and blended therapy are used interchangeably throughout the manuscript (also blend therapy, line 93). I think it would enhance the readability if authors clarify what they refer to with both concepts, or to stick with only one of them.

7. Also as a minor point on the fluency of language; the sentence in line 75 – 79 I would consider rephrasing. Line 89-90 “it seems…” As a reader I am confused as to what “it” refers to. It is probably better to use AFIs/blended psychotherapy/ psychotherapists.

**********

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Reviewer #1: Yes: Dr. Giovanni Rubeis

Reviewer #3: Yes: Maria Fogelkvist

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PLoS One. 2020 Aug 12;15(8):e0236995. doi: 10.1371/journal.pone.0236995.r004

Author response to Decision Letter 1


25 May 2020

Point-to-point reply to reviewers´ comments on our revised manuscript:

“Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended psychotherapy”

Changes in the revised manuscript are highlighted.

Reviewer #1: All comments have been addressed by the authors. The paper is acceptable for publication in its present form

Note: Thanks for your time and your helpful comments!

Reviewer #3: This is an interesting article to read, pointing to the importance of acceptance for blended psychotherapy in the treatment giver rather than receiver. Authors have made an effort to improve the manuscript by carefully considering previous reviewers comments. However, there are some points that I think still needs to be addressed.

1. Measures. The questionnaire used in this article, as well as its origins from UTAUT should be more thoroughly described in the method section. Readers who are unfamiliar with this instrument should be provided with enough information to evaluate the applicability of it. For instance, it would be helpful if you added more details on the original instrument, such as total amount of items and number of factors. Please describe how items (or factors) were chosen from the UTAUT, and in what manner they were adapted from the original version (such as; if items are rephrased completely, or adapted by changing some words in the items, and why inverted items were added). If your version is currently being evaluated for psychometric properties, it would be helpful if you mention this in the manuscript. Further, it is unclear where the items on internet anxiety were derived from; the UTAUT or developed by authors?

Note: Added to the manuscript (see amendments to “Measures – paragraphs “Primary outcome” and “secondary outcome”).

Since the result section describes deviance from the scale mean, the scale mean should also be stated here (or in the result section if you are referring to the mean of the study sample).

Note: Added to the manuscript (mean and range)

2. Materials and methods. It should be more clearly stated when data was collected, this will make the result section easier to understand, that results are exploring differences after manipulation, not baseline. (You provided this clearly in your answer to reviewer 2, however it is not as clearly described in the article).

Note: Added to the methods section (p. 8 “Acceptance was assessed after participants watched the intervention (IG) or attention placebo video (CG).”)

3. Data analysis. Authors describe splitting acceptance in three categories (low/medium/high), for descriptive purposes. Could you clarify how you decided on these cut-offs? Are they based on the distribution of responses? Or theoretically derived? Is there any reason not to analyze difference in distributions on acceptance statistically? I think that a chi-square test would be informative on difference in level of acceptance. (seems to be a typo in the medium range where I suppose the range is above 9 and below 16? line 189)

Note: we added chi-square. The authors, corresponding to prior publications on this scale, have defined the cut-off values based on a theoretical basis. We added this information to the manuscript.

4. In the result section you start by describing a rather high dropout rate in the intervention group. I think the article would benefit from an analysis on difference in characteristics between those who dropped out and those who were completers. This would give a hint if there is a bias in the study sample, if those who dropped out were mostly men, mostly from a specific therapeutic background and so on.

Note: We additionally ran all analysis based on multiple imputed data. For the imputation models we followed the recommendations by van Buuren and Groothuis-Oudshoorn (2011). Imputation models included: predictors included based on theoretical considerations, correlations between variables and correlations with non-response. Given this procedure gender or therapeutic background (or any other variable) which is associated with drop-out was included in the imputation. Since, the analysis using multiple imputations yielded no difference a systematic bias/ influence is unlikely.

van Buuren S, Groothuis-Oudshoorn K. mice : Multivariate Imputation by Chained Equations in R. J Stat Softw [Internet]. 2011;45(3).

5. In Table 2 it seems as if there is a difference in distribution of gender between groups, with a higher ratio of women to men in the intervention group as compared to control group. Have you checked if this (or other demographics) is a statistically significant difference in distribution? Thoughts on implications if so? (In my version the tab-spacing made table 2 almost uninterpretable, be sure to double-check this before publication).

Note: We did not run statistical tests examining potential baseline imbalance, thereby following CONSORT statement recommendations (Moher et al. 2010). However, we agree that there might be a gender imbalance, hence, we added this potential risk of bias to the limitation section of our manuscript.

Moher et al. ConSoRT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ 2010;340:c869

p. 17: “Third, there might be a baseline imbalance between the experimental conditions regarding gender, which could have biased the present findings. As the more important it seems to replicate the present findings in further experimental studies in order to substantiate the present evidence.”

6. The concept of blended psychotherapy and blended therapy are used interchangeably throughout the manuscript (also blend therapy, line 93). I think it would enhance the readability if authors clarify what they refer to with both concepts, or to stick with only one of them.

Note: we now use the term “blended therapy” throughout the manuscript.

7. Also as a minor point on the fluency of language; the sentence in line 75 – 79 I would consider rephrasing. Line 89-90 “it seems…” As a reader I am confused as to what “it” refers to. It is probably better to use AFIs/blended psychotherapy/ psychotherapists.

Note: Changed, thanks.

Thanks to all reviewers for their valuable time and insights!

Attachment

Submitted filename: Baumeister_Blended Therapy AFI_P2P reply revision2.docx

Decision Letter 2

Stephan Doering

11 Jun 2020

PONE-D-20-00142R2

Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended therapy

PLOS ONE

Dear Dr. Baumeister,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that your manuscript is very cloce to acceptance. Since reviewer 1 is completely satisfied with you revision of the previous version of ypou manuscript, reviewer 3 raises some minor concerns. I assume, that it will not cause too much effort to include these few changes. Therefore, we invite you to submit another revised version of the manuscript that addresses the points raised during the review process.

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We look forward to receiving your revised manuscript.

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Academic Editor

PLOS ONE

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While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2020 Aug 12;15(8):e0236995. doi: 10.1371/journal.pone.0236995.r006

Author response to Decision Letter 2


16 Jul 2020

Dear Editors,

thanks for inviting us to revise our manuscript. I just can´t find the reviewer 3 minor comments. There was no link and no attachment and I can´t find any information in the online submission system. What do I miss here?

Best wishes,

Harald Baumeister

Attachment

Submitted filename: Baumeister_Blended Therapy AFI_P2P reply revision2.docx

Decision Letter 3

Stephan Doering

20 Jul 2020

Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended therapy

PONE-D-20-00142R3

Dear Dr. Baumeister

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Stephan Doering, M.D.

Academic Editor

PLOS ONE

Acceptance letter

Stephan Doering

24 Jul 2020

PONE-D-20-00142R3

Impact of an acceptance facilitating intervention on psychotherapists’ acceptance of blended therapy

Dear Dr. Baumeister:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Professor Stephan Doering

Academic Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Video script.

    (DOCX)

    S2 File. Dataset.

    (XLSX)

    Attachment

    Submitted filename: Baumeister_Blended Therapy AFI_P2P reply.docx

    Attachment

    Submitted filename: Baumeister_Blended Therapy AFI_P2P reply revision2.docx

    Attachment

    Submitted filename: Baumeister_Blended Therapy AFI_P2P reply revision2.docx

    Data Availability Statement

    All relevant data are within the manuscript and its Supporting Information files.


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