3.
小鼠血浆中UV-327和UV-328稳定性实验结果(n=6)
Stability test results of UV-327 and UV-328 in mice plasma (n=6)
| Analyte | Spiked concentration/ (mg/L) |
Instant | Room temperature for 6 h | -40 ℃ for 15 d | |||
| Measured concentration/ (mg/L), x±s |
Measured concentration/ (mg/L), x±s |
Relative deviation | Measured concentration/ (mg/L), x±s |
Relative deviation | |||
| UV-327 | 0.50 | 0.45±0.01 | 0.45±0.01 | 0.9% | 0.51±0.04 | 13.3% | |
| 1.00 | 0.95±0.04 | 0.94±0.01 | 1.1% | 0.88±0.02 | 7.4% | ||
| 2.00 | 2.00±0.04 | 1.93±0.17 | 3.5% | 1.70±0.04 | 15.0% | ||
| UV-328 | 0.50 | 0.47±0.01 | 0.49±0.02 | 4.3% | 0.46±0.01 | 2.1% | |
| 1.00 | 1.02±0.02 | 1.04±0.04 | 2.0% | 0.92±0.02 | 9.8% | ||
| 2.00 | 2.10±0.05 | 2.03±0.13 | 3.3% | 1.81±0.05 | 13.8% | ||