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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Traffic. 2020 Jul;21(7):463–478. doi: 10.1111/tra.12734

Table 2.

Numbering of homologous key residues in Dm BicD and Hs BicD2

Dm BicD Hs BicD2
Conversion for residue # Residue i Residue i+59
N-terminal dynein/dynactin binding site 21–380 11 1-400 5
C-terminal cargo-binding domain (CTD) 656-745 9 715-804 30
Dm BicD/F684I mutant F684I F743I
Key aromatic residues F684, F691, Y698 F743, F750, Y757
Nup358 interface residues* L687, R688, M690, R694 L746, R747, M749, R753
*

Interface residues and dynein/dynactin binding site were mapped for Ms BicD1, a close homolog of Hs BicD2.5,10 Residue i of Hs BicD2 (as listed in the table) is homologous to residue i-2 of Ms BicD1.