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letter . 2020 Aug 7:pvaa098. doi: 10.1093/ehjcvp/pvaa098
The association of hypertension and diabetes pharmacotherapy with COVID-19 severity and immune signatures: an observational study
Rinkoo Dalan
1,✉, Li Wei Ang
2, Wilnard Y T Tan
2, Siew-Wai Fong
3, Woo Chiao Tay
2, Yi-Hao Chan
4, Laurent Renia
4, Lisa F P Ng
4, David Chien Lye
5, Daniel E K Chew
1, Barnaby E Young
5
Dr Rinkoo Dalan, FRCP
1Department of Endocrinology, Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. 11 Jalan Tan Tock Seng Singapore
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Ms Li Wei Ang, MSc
2
National Centre for infectious diseases. 16 Jalan Tan Tock Seng, Singapore
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Dr Wilnard Y T Tan, MBBS
2
National Centre for infectious diseases. 16 Jalan Tan Tock Seng, Singapore
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Dr Siew-Wai Fong, PhD
3Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648; Department of Biological Sciences, National University of Singapore, Singapore
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Dr Woo Chiao Tay, MBBS
2
National Centre for infectious diseases. 16 Jalan Tan Tock Seng, Singapore
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Dr Yi-Hao Chan, PhD
4Singapore Immunology Network, Agency for Science, Technology and Research, Singapore
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Laurent Renia, PhD
4Singapore Immunology Network, Agency for Science, Technology and Research, Singapore
Professor
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Lisa F P Ng, PhD
4Singapore Immunology Network, Agency for Science, Technology and Research, Singapore
Professor
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David Chien Lye, FRACP
5
National Centre for Infectious Diseases. Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. Yong Loo Lin School of Medicine. 16 Jalan Tan Tock Seng, Singapore
Associate Professor
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Daniel E K Chew, FRCP
1Department of Endocrinology, Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. 11 Jalan Tan Tock Seng Singapore
Associate Professor
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Dr Barnaby E Young, BM BChir
5
National Centre for Infectious Diseases. Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. Yong Loo Lin School of Medicine. 16 Jalan Tan Tock Seng, Singapore
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1Department of Endocrinology, Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. 11 Jalan Tan Tock Seng Singapore
2
National Centre for infectious diseases. 16 Jalan Tan Tock Seng, Singapore
3Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648; Department of Biological Sciences, National University of Singapore, Singapore
4Singapore Immunology Network, Agency for Science, Technology and Research, Singapore
5
National Centre for Infectious Diseases. Tan Tock Seng Hospital. Lee Kong Chian School of Medicine. Yong Loo Lin School of Medicine. 16 Jalan Tan Tock Seng, Singapore
✉
Corresponding Author : Rinkoo Dalan, Department of Endocrinology, Tan Tock Seng Hospital, Lee Kong Chian School of Medicine, 11 Jalan Tan Tock Seng, Singapore 308433. Email: Rinkoo_dalan@ttsh.com.sg, Phone no: 65-63571000
Roles
Laurent Renia: PhD, Professor
Lisa F P Ng: PhD, Professor
David Chien Lye: FRACP, Associate Professor
Daniel E K Chew: FRCP, Associate Professor
Received 2020 Jul 7; Revised 2020 Jul 21; Accepted 2020 Jul 23.
Keywords: hypertension, diabetes, angiotensin-converting enzyme inhibitors (ACE-I), Angiotensin receptor blocker (ARB), dipeptidyl peptidase 4 inhibitors (DPP4i)
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PMCID: PMC7454507 PMID: 32766831