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AXT201 inhibits VEGFR2, cMet, and IGF1 R signaling. (a-c) Top – Western blot images showing changes in the phosphorylation of (a) VEGFR2, (b) cMet, and (c) IGF1 R in HUVECs exposed to VEGFA, HGF, or IGF1 respectively and varying concentrations of AXT201. GAPDH and αTubulin are provided as loading controls. Bottom – quantification of band intensities normalized for loading and presented as percentages of growth factor only controls.
