Structural and functional analysis of hemostatic agents in diluted neonatal porcine plasma. Representative images are shown of diluted neonatal porcine plasma in the absence or presence of FEIBA, factor VII (rFVIIa), or platelet-like particles (PLPs) (A). Average clot fiber density (B), alignment (C), and clottability (D) are reported +/− standard deviation. Structural analysis: plasma: N=7, FEIBA, factor VII, RiaSTAP, platelet-like particles: N=5. Clottability: platelet poor plasma: N=6, FEIBA, factor VII, RiaSTAP, platelet-like particles: N= 5 *p<0.05, **p<0.01.