Table 2.

Evaluation of the performance of the captopril release profiles in simulated saliva (Pk-Solver). AIC: Akaike Information Criterion.

Parameter	Order I	Higuchi	Korsmeyer-Peppas	Weibull
K	k1 = 0.143	kH = 18.154	kKP = 59.120	a = 2.934
Tlag	0.487	‒4.285	4.765	Ti = 2.614
			n = 0.160	β = 0.713
N_obs	5	5	5	5
Degrees of Freedom	3	3	2	2
Observed correlation coefficient R	0.997	0.922	0.998	0.999
R2	0.994	0.849	0.997	0.998
R2 adjusted	0.993	0.798	0.995	0.996
Mean Square Error	2.83	82.45	1.73	1.32
Sum of squared errors	8.49	247.36	3.46	2.64
AIC	14.69	31.55	12.21	10.86