Table 2.
Proteins listed in the four canonical pathways with statistically significant z-score.
| Symbol | Entrez Gene Name | UniProt Accession | q-Value | Fold Change | Pathway |
|---|---|---|---|---|---|
| PTPA | protein phosphatase 2 phosphatase activator | PTPA_HUMAN | 3.82 × 10−5 | 1.44 | ILK |
| VIM | vimentin | VIME_HUMAN | 1.16 × 10−4 | 1.40 | |
| ITGB1 | integrin subunit beta 1 | ITB1_HUMAN | 3.26 × 10−3 | 1.38 | |
| CDC42 | cell division cycle 42 | CDC42_HUMAN | 5.28 × 10−3 | 1.22 | |
| MYH9 | myosin heavy chain 9 | MYH9_HUMAN | 2.27 × 10−3 | −1.31 | |
| MYL6 | myosin light chain 6 | MYL6_HUMAN | 2.05 × 10−2 | −1.31 | |
| NACA | nascent polypeptide associated complex subunit alpha | NACAM_HUMAN | 1.00 × 10−3 | −1.47 | |
| PARVA | parvin alpha | PARVA_HUMAN | 4.29 × 10−4 | −1.47 | |
| CFL1 | cofilin 1 | COF1_HUMAN | 3.53 × 10−3 | −1.50 | |
| ACTB | actin beta | ACTB_HUMAN | 3.82 × 10−5 | −1.52 | |
| CTNNB1 | catenin beta 1 | CTNB1_HUMAN | 5.75 × 10−4 | −1.64 | |
| MYL9 | myosin light chain 9 | MYL9_HUMAN | 3.16 × 10−4 | −1.73 | |
| CFL2 | cofilin 2 | COF2_HUMAN | 1.32 × 10−3 | −1.73 | |
| PPP1R12A | protein phosphatase 1 regulatory subunit 12A | MYPT1_HUMAN | 1.04 × 10−3 | −1.86 | |
| FLNC | filamin C | FLNC_HUMAN | 4.22 × 10−4 | −1.95 | |
| FN1 | fibronectin 1 | FINC_HUMAN | 1.62 × 10−5 | −3.31 | |
| ACAA2 | acetyl-CoA acyltransferase 2 | THIM_HUMAN | 3.67 × 10−4 | 1.82 | βOX |
| HADH | hydroxyacyl-CoA dehydrogenase | HCDH_HUMAN | 1.80 × 10−2 | 1.82 | |
| HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | ECHB_HUMAN | 2.57 × 10−4 | 1.49 | |
| HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | ECHA_HUMAN | 2.46 × 10−2 | 1.48 | |
| CS | citrate synthase | CISY_HUMAN | 7.93 × 10−3 | 1.72 | TCA |
| MDH2 | malate dehydrogenase 2 | MDHM_HUMAN | 4.67 × 10−3 | 1.57 | |
| OGDH | oxoglutarate dehydrogenase | ODO1_HUMAN | 6.99 × 10−3 | 1.53 | |
| DLST | dihydrolipoamide S-succinyltransferase | ODO2_HUMAN | 1.08 × 10−3 | 1.21 | |
| RAC1 | Rac family small GTPase 1 | RAC1_HUMAN | 1.06 × 10−2 | 1.35 | GP6 |
| COL6A2 | collagen type VI alpha 2 chain | CO6A2_HUMAN | 1.07 × 10−3 | −1.22 | |
| COL6A3 | collagen type VI alpha 3 chain | CO6A3_HUMAN | 2.43 × 10−2 | −1.40 | |
| COL6A1 | collagen type VI alpha 1 chain | CO6A1_HUMAN | 1.60 × 10−4 | −2.76 | |
| TLN1 | talin 1 | TLN1_HUMAN | 3.00 × 10−4 | −3.70 | |
| COL12A1 | collagen type XII alpha 1 chain | COCA1_HUMAN | 1.04 × 10−4 | −4.90 | |
| COL1A2 | collagen type I alpha 2 chain | CO1A2_HUMAN | 1.34 × 10−5 | −7.38 | |
| COL1A1 | collagen type I alpha 1 chain | CO1A1_HUMAN | 1.49 × 10−3 | −11.06 |
ILK: Integrin-linked kinase signalling; βOX: Fatty acid β oxidation; TCA: Tricarboxylic acid cycle; GP6: Glycoprotein VI signalling pathway.