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. 2020 Aug 27;6(8):e04623. doi: 10.1016/j.heliyon.2020.e04623

Table 7.

Generation of diverse types of immunologically reactive molecules from various native biochemical constituents upon treatment with exogenous and endogenous substances.

[S. No.] Source Identity of target molecules Treatment with exogenous/endogenous substances Activity generated References
1. Bovine and human milk Lactoferrin Pepsin Antibacterial Bellamy et al. (1992)
2. Hen eggs Egg white lysozyme Dimethyl suberimidate Lectin-like Mega and Hase (1994)
Egg white lysozyme Clostripain Antibacterial Pellegrini et al. (1997)
Egg white lysozyme Trypsin, chymotrypsin, pepsin Antiviral Overmann et al. (2003)
Egg white lysozyme Pepsin → trypsin Antibacterial Mine et al. (2004)
Ovalbumin Trypsin, chymotrypsin Antibacterial Pellegrini et al. (2004)
Antifungal
3. Bovine milk Casein Trypsin, pronase, Antibacterial Zucht et al. (1995)
endoproteinase Glu C
4. Bovine milk Casein Chymosin Antibacterial Lahov and Regelson, 1996
Immunostimulatory
5. Bovine milk β-lactoglobulin Trypsin Antibacterial Pellegrini et al. (2001)
6. Bovine serum Albumin Trypsin, chymotrypsin, pepsin Antiviral Overmann et al. (2003)
7. Rabbit milk (Oryctolagus cuniculus) Casein Trypsin, chymotrypsin, pepsin, clostripain Antibacterial Baranyi et al. (2003)
8. Human Serum Human serum Albumin Pronase Hemagglutinating and Phenoloxidase activity Beulaja and Manikandan, 2012a, Beulaja and Manikandan, 2012b