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. 2020 Apr 22;43(5):1611–1619. doi: 10.1007/s10753-020-01236-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Characterization of M-EVs. a Electron micrograph of M1-EVs and M0-EVs shows a circular and double-membrane structure. b The size distribution and total number of EVs from M1 and M0 were measured by nanoparticle tracking analysis. c The presence of the EVs protein markers Tsg101, CD63, histone H3, and GAPDH; M1-P and M0-P stand for pellet from the 5000×g spin of M1-EVs and M0-EVs group, respectively.