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. 2019 Sep 17;10(11):1935–1947. doi: 10.1039/c9md00173e

Scheme 2. Reagents and conditions: (a) Ar2, NaH, DMF, 0 °C, 30–50 min; (b) BrCH2COOBu-t, 50 °C, 12 h; (c) CF3COOH, CH2Cl2, room temperature, 16 h; (d) DMF, EDC·HCl, DMAP, 0 °C, 30 min; (e) nitrogenous compounds, room temperature, overnight.

Scheme 2