Liposomes are biocompatible, biodegradable, and nontoxic vesicles able to encapsulate and carry drugs, and have been used in a broad range of pharmaceutical applications, including for nebulized antibiotic delivery

Use of inhaled liposomal antimicrobial treatment in lung Infections results in targeting of the antimicrobial agent at the site of infection to the infectious organism, increasing intracellular antibiotic concentrations, reducing drug toxicity, and improving tolerability

The most important liposomal antimicrobial drugs for inhalation include amikacin, tobramycin, ciprofloxacin, and amphotericin B

New avenues of research in the delivery of lung-targeted liposomal antimicrobials alone or in association with other treatment alternatives are being investigated