Abstract
Cytomegalovirus (CMV) is the leading cause of congenital infection and the most common cause of non-genetic sensorineural hearing loss (SNHL) in childhood. Although most infected infants are asymptomatic at birth, the risk for SNHL and other neurodevelopmental morbidity makes congenital CMV (cCMV) a disease of significance. Adherence to hygienic measures in pregnancy can reduce risk for maternal CMV infection. The prompt identification of infected infants allows early initiation of surveillance and management. A multidisciplinary approach to management is critical to optimize outcomes in affected infants.
Keywords: Congenital infection, Cytomegalovirus (CMV), Neurodevelopmental sequelae, Polymerase chain reaction (PCR), Sensorineural hearing loss (SNHL), Valganciclovir
CANADIAN PAEDIATRIC SOCIETY INFECTIOUS DISEASES AND IMMUNIZATION COMMITTEE
Members: Michelle Barton MD, A. Michael Forrester MD (past member), Ruth Grimes MD (Board Representative), Nicole Le Saux MD (Chair), Laura Sauvé MD, Karina Top MD
Liaisons: Tobey Audcent MD, Committee to Advise on Tropical Medicine and Travel (CATMAT), Public Health Agency of Canada; Sean Bitnun MD, Canadian Pediatric and Perinatal HIV/AIDS Research Group; Fahamia Koudra MD, College of Family Physicians of Canada; Marc Lebel MD, IMPACT (Immunization Monitoring Program, ACTIVE); Yvonne Maldonado MD, Committee on Infectious Diseases, American Academy of Pediatrics; Jane McDonald MD, Association of Medical Microbiology and Infectious Disease Canada; Dorothy L. Moore MD, National Advisory Committee on Immunization (NACI); Howard Njoo MD, Public Health Agency of Canada
Consultant: Noni E. MacDonald MD
Principal authors: Michelle Barton MD, A. Michael Forrester MD, Jane McDonald MD
Correspondence: Canadian Paediatric Society, 100-2305 St Laurent Blvd, Ottawa, Ontario K1G 4J8. E-mail info@cps.ca
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