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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Sep 5:ciaa1338. doi: 10.1093/cid/ciaa1338

SARS-CoV-2 RNA in plasma is associated with ICU admission and mortality in patients hospitalized with COVID-19

Christian Prebensen 1,2, Peder L My hre 2,3, Christine Jonassen 4, Anbjørg Rangberg 4, Anita Blomfeldt 5, My Svensson 6, Torbjørn Omland 2,3, Jan-Erik Berdal 1,2,
PMCID: PMC7499533  PMID: 32888003

Abstract

The clinical significance of SARS-CoV-2 RNA in the circulation is unknown. In this prospective cohort study, we detected viral RNA in the plasma of 58/123 (47%) patients hospitalized with COVID-19. RNA was detected more frequently, and levels were higher, in patients who were admitted to the ICU and/or died.

Keywords: SARS-CoV-2, COVID-19, RNAemia, viral load, antibodies


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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