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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Aug 28:ciaa1286. doi: 10.1093/cid/ciaa1286

Using Serologic Testing to Assess the Effectiveness of Outbreak Control Efforts, Serial PCR Testing, and Cohorting of Positive SARS-CoV-2 Patients in a Skilled Nursing Facility

Amy V Dora 1,#,, Alexander Winnett 1,#, Jennifer A Fulcher 1,2, Linda Sohn 3, Feliza Calub 2, Ian Lee-Chang 2, Elham Ghadishah 3, William A Schwartzman 2, David O Beenhouwer 2, John Vallone 4, Christopher J Graber 2, Matthew Bidwell Goetz 2, Debika Bhattacharya 1,2
PMCID: PMC7499538  PMID: 32857830

Abstract

We characterized serology following a nursing home outbreak where residents were serially tested by RT-PCR and positive residents were cohorted. When tested 46-76 days later, 24/26 RT-PCR-positive residents were seropositive; none of the 124 RT-PCR-negative residents had confirmed seropositivity, supporting serial SARS-CoV-2 RT-PCR testing and cohorting in nursing homes.

Keywords: COVID-19, SARS-CoV-2 serology, long-term care facility, infection control


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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