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Demonstration of the active site residues when a statin (atorvastatin) is bounded (PDB code 1HWK): (a) only atorvastatin is presented in yellow; and (b) HMG-CoA is also bound to more easily compare the inhibitor with the natural substrate (PDB entry 1HWK and 1DQ9). These structures follow the representation and color code of the dimer in Figure 6, as chain A and B are colored in magenta and blue (transparent to better see details), respectively.
