Table 4.
Medications upon hospital discharge
| Medications | Sleep apnoea (n=504) |
Non-sleep apnoea (n=489) |
P value |
| Aspirin | 467 (92.7) | 441 (90.2) | 0.16 |
| Dual antiplatelet therapy | 386 (76.6) | 392 (80.2) | 0.17 |
| β-blocker | 457 (90.7) | 441 (90.2) | 0.79 |
| ACEI/ARB | 176 (34.9) | 169 (34.6) | 0.91 |
| Statin | 489 (97.0) | 480 (98.2) | 0.24 |
| Ezetimibe | 11 (2.2) | 7 (1.4) | 0.38 |
| Fibrates | 12 (2.4) | 8 (1.6) | 0.40 |
| Oral anticoagulant | 83 (16.5) | 45 (9.2) | 0.0010 |
| Warfarin* | 66 (13.1) | 37 (7.6) | 0.0040 |
| Direct oral anticoagulant† | 17 (3.4) | 8 (1.6) | 0.081 |
| Frusemide | 302 (59.9) | 240 (49.1) | 0.0010 |
| Spironolactone | 40 (7.9) | 18 (3.7) | 0.0040 |
*Indications (warfarin, sleep apnoea group): atrial fibrillation (n=29, 43.9%), endarterectomy (n=20, 30.3%), valve replacement (n=12, 18.2%), miscellaneous (n=5, 7.6%; left ventricular thrombus=4, antiphospholipid syndrome=1). Indications (warfarin, non-sleep apnoea group): atrial fibrillation (n=21, 56.8%), endarterectomy (n=11, 29.7%), valve replacement (n=3, 8.1%), multiple old strokes (n=2, 5.4%).
†Indications (direct oral anticoagulant, sleep apnoea group): atrial fibrillation for all.
ACEI, ACE inhibitor; ARB, angiotensin receptor blocker.