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. 2020 Sep 25;160(1):287–301.e20. doi: 10.1053/j.gastro.2020.09.029

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© 2021 by the AGA Institute.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Robust ACE2 expression is found on small bowel surface epithelium in both children and adults. Representative immunofluorescence images of ACE2 (green) and EPCAM (red) counterstained with DAPI (blue) in intestinal biopsies of healthy patients, including magnified images of surface epithelium (se) and crypt epithelium (ce). (A) Duodenal biopsies, (B) terminal ileum biopsies (Goblet cell indicated with arrow and (C) colonic biopsies from indicated sites. Patient age (years) and sex (M, male; F, female) as indicated. Isotype controls and no primary controls for each segment are included on the far right of each panel. Scale bar, 100 μm.