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Mean DNA methylation and variability distinguishes IBD from healthy intestinal epithelial cells.
(a) Top differentially variable methylated CpG sites (DVMCs) in IBD vs. Control. DNA methylation was plotted as beta values for each of the top nine DVMC identified with the iEVORA algorithm (see Methods section). (b) Gene symbols overlapping between site- (DMPs), region (DMRs)-level, and variability (DVMCs) analyses.
