Skip to main content
BioMed Research International logoLink to BioMed Research International
. 2020 Sep 19;2020:8493938. doi: 10.1155/2020/8493938

Erratum to “An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation”

Ruijin Liu 1, Si-cong Wang 1, Ming Li 2, Xiao-hui Ma 3, Xiao-nan Jia 3, Yue Bu 1, Lei Sun 1, Kai-jiang Yu 3,4,
PMCID: PMC7520697  PMID: 33015183

In the article titled “An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation” [1], the published version of Figure 4(a) was a duplicate of Figure 2(a). This mistake was introduced during the production of the article, and the publisher apologises for this error.

The corrected figure is shown below and is listed as Figure 1.

Figure 1.

Figure 1

S-AKI cell model shows that DRP1 inhibition attenuates renal tubular epithelial pyroptosis and protects mitochondrial function by NLRP3 inflammasome pathway protein expression downregulation. (a) Western blot protein expression bands of the NLRP3 inflammasome-related proteins, NLRP3, GSDMD, cl. caspase-1, IL-1β, and IL-18. (b) Semiquantitative analysis of Western blot protein expression bands of the NLRP3 inflammasome-related proteins. (c) JC-1 staining of cells, where the color red represents the membrane potential level. Image obtained under a confocal microscope (20x magnification). (d) MitoSOX staining of cells, where the color red represents the superoxidation level. Image obtained under a confocal microscope (60x magnification). (e) Quantitative analysis of JC-1 staining. (f) Quantitative analysis of MitoSOX staining. (g) Intracellular ATP levels in different treatment groups. n = 6 for each group in all experiments. The data are presented as means ± SEM. P < 0.05 versus control-treated cells. #P < 0.05 versus LPS-treated cells in the absence of Mdivi-1 treatment.

References

  • 1.Liu R., Wang S.-c., Li M., et al. An inhibitor of DRP1 (Mdivi-1) alleviates LPS-induced septic AKI by inhibiting NLRP3 inflammasome activation. BioMed Research International. 2020;2020:11. doi: 10.1155/2020/2398420.2398420 [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from BioMed Research International are provided here courtesy of Wiley

RESOURCES