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. 2020 Oct 5;3(5):1589–1600. doi: 10.1016/j.matt.2020.09.021

Figure 1.

Figure 1

Scheme of an MN/Ab Swab Synergistically Providing Mucus Penetration and Virus Extraction for Highly Efficient COVID-19 Detection

After inserting into the oral cavity and contacting with posterior pharynx and tonsillar areas, the MN/Ab swab was rotated to guarantee differently crosslinked MNs touching the tissue for 5–10 s. SARS-CoV-2 would self-accumulate around and in the MNs as a result of antigen-antibody interactions. In such a way, a more specific and effective sampling was achieved.