Table 1. Comparison of three major orthology databases with the BigWenDB.
The number of species of a given taxon (left column) in four different orthology databases is shown. In contrast to other databases, the BigWenDB has substantially more sequence information from non-bilaterian metazoans and therefore a better resolution at the divergence of bilaterians and non-bilaterians. D = Deuterostomia, E = Ecdysozoa. Note the bias of other databases towards insects and vertebrates, which continues in the latest database versions (e.g., OrthoDB v10.2; Kriventseva et al., 2019).
| Taxon | OrthoDB V8 | eggNOG V4.5 | OrthoMCL V5 | BigWenDB |
|---|---|---|---|---|
| Cellular organisms | 3,027 | 2,031 | 150 | 273 |
| Metazoa | 173 | 88 | 29 | 175 |
| Bilateria | 169 | 85 | 27 | 142 |
| non-Bilateria | 4 | 3 | 2 | 33 |
| Ecdysozoa (E) | 97 | 29 | 12 | 54 |
| E w/o insects | 17 | 9 | 4 | 29 |
| Lophotrochozoa | 5 | 0 | 0 | 18 |
| Deuterostomia (D) | 66 | 55 | 14 | 65 |
| D w/o vertebrates | 5 | 4 | 1 | 12 |