Figure 3. ¹⁸F-flortaucipir binding and Free and Cued Selective Reminding Test score.

Black circles represent noncarriers; red circles represent cognitively unimpaired PSEN1 mutation carriers. Unfilled red circles represent mutation carriers with mild cognitive impairment. (A) Free recall (FR) scores significantly predict tau burden in the entorhinal cortex. (B) There is no association between total recall (TR) and tau in the entorhinal cortex. (C) FR scores significantly predict tau burden in the inferior temporal cortex. (D) There is no association between TR and tau burden in the inferior temporal cortex.