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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Sep 28:ciaa1463. doi: 10.1093/cid/ciaa1463

Assessment of the Haemophagocytic lymphohistiocytosis HScore in patients with COVID-19

Kristina E N Clark 1,, William D Nevin 2, Tabitha Mahungu 2, Helen Lachmann 3, Animesh Singh 4
PMCID: PMC7543356  PMID: 32985664

Abstract

The clinical manifestation of moderate to severe COVID-19 has parallels to secondary haemophagocytic lymphohistiocytosis (HLH) both clinically and based on molecular inflammatory response. We found no evidence to support the utility of risk stratifying COVID-19 patients using risk scoring methodology designed for HLH.

Keywords: HLH, COVID-19, HScore, cytokine storm


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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