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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Sep 30:deaa284. doi: 10.1093/humrep/deaa284

Undetectable viral RNA in oocytes from SARS-CoV-2 positive women

M Barragan 1, J J Guillén 1, N Martin-Palomino 1, A Rodriguez 1, R Vassena 1,
PMCID: PMC7543480  PMID: 32998162

Abstract

A central concern for the safe provision of ART during the current coronavirus disease 2019 (CODIV-19) pandemic is the possibility of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through gametes and preimplantation embryos. Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected individuals are not available to date. We describe the case of two women who underwent controlled ovarian stimulation and tested positive to SARS-CoV-2 infection by PCR on the day of oocyte collection. The viral RNA for gene N was undetectable in all the oocytes analyzed from the two women.

Keywords: coronavirus, COVID-19, oocyte, SARS-CoV-2, IVF, ICSI, ovarian stimulation


Articles from Human Reproduction (Oxford, England) are provided here courtesy of Oxford University Press

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