Abstract
In the fight against epidemic infectious diseases in the past 2,000 years, Chinese medicine (CM) has gradually developed a complete response system including diagnosis and treatment. The focal point of CM in the treatment of infectious diseases is the personalized response state to pathogen, which is a treatment method consistent with the personalized concept of precision medicine. Compared with the methods of directly killing or inactivating pathogens, which are used in modern medicine, CM is an effective treatment modality that has a wider range of points of action in the human body. The remarkable effects achieved while treating SARS in 2003 and the current coronavirus disease 2019 (COVID-19) pneumonia and the history of the effective responses to epidemics in the past 2,000 years have fully demonstrated the effectiveness of CM in treating infectious diseases. This article discusses the different treatment mechanisms for infectious diseases in CM and modern medicine and the advantages of CM methods, which will reacquaint the world with CM. The improvement of the diagnosis and treatment system of CM based on scientific concepts and methods and the organic combination of both treatment methods of modern medicine and CM will provide the best solution for humans to defeat epidemic infectious diseases.
Keywords: COVID-19, coronavirus, infectious disease, epidemic, Chinese medicine, SARS-CoV-2
References
- 1.Breaking news. Researchers from multiple countries claim that the new coronavirus has mutated. March 5, 2020. Available at https://news.rthk.hk/rthk/ch/component/k2/1512595-20200305.htm
- 2.Reporters Tian XH and Wen JH. TCM can play a full role in the prevention and treatment of COVID-19 pneumonitis—Interview with Academician ZHANG Bo-li, expert of National Scientific Research Expert Group. Xinhua News Agency, Beijing, Jan 27, 2020. Available at http://www.xinhuanet.com/2020-01/27/c_1125505871.htm
- 3.Liang Q. Integrated traditional Chinese and Western medicine for COVID-19 pneumonia. Xinhuanet, Feb 12, 2020. Available at http://www.xinhuanet.com/politics/2020-02/12/c_1125561735.htm
- 4.Huang B, Chen LJ, Suo XC. Let all diagnosed patients use TCM. China Traditional Chinese Medicine Network, Feb 14, 2020. Available at http://www.cntcm.com.cn/2020-02/14/content_71210.htm
- 5.Wu Q. 29 patients with COVID-19 pneumonia in Shanxi were cured and discharged after integrated Chinese and Western medicine treatment. China News Network, Feb 12, 2020. Available at https://m.chinanews.com/wap/detail/zw/sh/2020/02-12/9089028.shtml
- 6.Guangdong Provincial Drug Administration. The Provincial Drug Administration intends to include the registration of preparations for medical institutions in the No. 8 People’s Hospital of Guangzhou “Pneumonia No.1” into the emergency approval. Feb 1, 2020. Available at http://mpa.gd.gov.cn/gkmlpt/contenf2/2881/post_2881418.html
- 7.Reporter Guo XY and Zhou Y. Guangdong: The designated hospitals in the province have used “Pneumonia No. 1” over 6,000 packets. Feb 9, 2020. Available at http://news.cnr.cn/native/city/20200219/t20200219_524982385.shtml
- 8.Reporter Yi YL. Hunan does have a set, in fighting against plague with TCM. Tencent, Feb 13, 2020. Available at https://new.qq.com/rain/a/20200213A0MTYO
- 9.Beijing Municipal Government Information Office. Beijing Ditan Hospital: 87.5% effective rate of traditional Chinese medicine plus symptomatic treatment, 92.3% effective rate of integrated traditional Chinese and Western medicine. Tencent, Feb 18, 2020. Available at https://new.qq.com/rain/a/20200215A0NQ3K00
- 10.Reporter Ma FC. TCM rescue and treatment of patients with COVID-19 pneumonia is promising. China Youth Daily, Mar 3, 2020. Available at http://www.xinhuanet.com/2020-03/03/c_1125657175.htm
- 11.Yuan B. Dawn of viral epidemic treatment: the medical system based on body states control. Ann Clin Lab Res. 2016;4:3. doi: 10.21767/2386-5180.1000116. [DOI] [Google Scholar]
- 12.Chang D, Xu HW, Rebaza A, Sharma L, Cruz CSD. Protecting health-care workers from subclinical coronavirus infection. Lancet Respir Med. 2020;8:e13. doi: 10.1016/S2213-2600(20)30066-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 13.Yu JM, Zheng HZ. 13 patients who were cured and discharged from hospital turned positive in nucleic acid and experts: whether it is contagious or not is uncertain. Southern Daily, Feb 25, 2020. Available at https://xw.qq.com/cmsid/20200225A0NG5B00
- 14.Yuan B. Ebola strikes, it is both a challenge and an opportunity. China Traditional Chinese Medicine News, Oct 20, 2014. 3rd Edition, Perspective.
- 15.General Office of the National Health Commission, Office of the State Administration of TCM. Notice on printing and distributing pneumonia diagnosis and treatment plan for new coronavirus infection (trial version 6), Feb 5, 2020. Available at http://yzs.satcm.gov.cn/zhengcewenjian/2020-02-19/13221.html
- 16.Liu QQ. First aid mainly depends on Western medicine? Wrong! Chinese medicine first aid is not optional, but essential! Daily Headlines, Mar 16, 2020. Available at https://kknews.cc/health/284ynxy.html
- 17.Cohen J. Can an anti-HIV combination or other existing drugs outwit the new coronavirus? Science, 2020. Available at 10.1126/science.abb0659
- 18.Qing GC, Zhang H, Bai Y, Luo Y. Traditional Chinese and Western medicines jointly beat COVID-19 pandemic. Chin J Integr Med. 2020;26:403–404. doi: 10.1007/s11655-020-3095-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Yang Q, Sun QG, Jiang B, Xu HJ, Luo M, Xie P, et al. Retrospective clinical study on treatment of COVID-2019 patients with integrated traditional Chinese and Western medicine. Chin Tradit Herb Drugs (Chin) 2020:1–5. Available at http://kns.cnki.net/kcms/detail/12.1108.R.20200413.1302.002.html
- 20.Song P, Zhao LH, Li XY, Su JS, Jiang ZY, Song B, et al. Interpretation of TCM part in diagnosis and treatment protocol for COVID-19 (trial version 7). J Tradit Chin Med 2020:1–41. Available at http://kns.cnki.net/kcms/detail/11.2167.R.20200325.1623.002.html [DOI] [PubMed]
- 21.Xia WG, An CQ, Zheng CJ, Zhang JX, Huang M, Wang Y, et al. Clinical observation on 34 patients with novel coronavirus pneumonia (COVID-19) treated with integrated traditional Chinese and Western medicine. J Tradit Chin Med. 2020;61:375–382. [Google Scholar]
- 22.Fu XX, Lin LP, Tan XH. Clinical study on 37 case of COVID-19 treated with integrated traditional Chinese and Western medicine. Tradit Chin Drug Res Clin Pharmacol (Chin) 2020:1–9. Available at http://kns.cnki.net/kcms/detail/44.1308.R.20200319.1644.002.html
- 23.Cui HT, Li YT, Guo LY, Liu XG, Wang LS, Jia JW, et al. Traditional Chinese medicine for treatment of coronavirus disease 2019: a review. Tradit Med Res. 2020;5:65–73. doi: 10.53388/TMR20200222165. [DOI] [Google Scholar]
- 24.Harper J. Coronavirus: will someone develop a vaccine? The BBC, Feb 13, 2020. Available at https://www.bbc.com/news/business-51454859
- 25.Reporter Li C. Scientists reveal important regulatory mechanism of cell “Door God” against viral infection. China News Network, Feb 23, 2019. Available at https://tech.huanqiu.com/article/9CaKrnKilTz
- 26.Yuan B. Precision medicine: to start the era of status medicine to be the mainstream. Avid Sci, 2016. Available at https://avidscience.com/book/precision-medicine-to-start-the-era-of-status-medicine-to-be-the-mainstream-medicine/
- 27.Yuan B. Toward holistic medicine and holistic biology: life sciences after precision medicine and systems biology. Front Life Sci. 2019;12:14–26. doi: 10.1080/21553769.2019.1682064. [DOI] [Google Scholar]
- 28.The ASCO Post. FDA approves larotrectinib for solid tumors with NTRK gene fusion. Dec 27, 2018. Available at https://ascopost.com/News/59498
- 29.Ashley EA. Towards precision medicine. Nat Rev Genet. 2016;17:507–522. doi: 10.1038/nrg.2016.86. [DOI] [PubMed] [Google Scholar]
- 30.American Society of Clinical Oncology. CancerLinQ partners with FDA to study real-world use of newly approved cancer treatments. Jun 1, 2017. Available at https://www.asco.org/about-asco
- 31.Gabay M. 21st century cures act. Hosp Pharm. 2017;52:264–265. doi: 10.1310/hpx5204-264. [DOI] [PMC free article] [PubMed] [Google Scholar]