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Immunohistochemistry performed on paraffin-embedded submandibular salivary glands. (A) Photomicrographs at 20× and 40× magnification for carboxymethyllysine (CML) immunopositivity, showing increased amounts in acini (#) and ducts (∗), as indicated by arrows, of the AGE-D mice. (B) Photomicrographs at 20× and 40× magnification for receptor for AGEs (RAGE) immunopositivity, which was increased in the myoepithelial and basal lamina of ducts as indicated by arrows.
