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. 2020 Oct 21;5(5):e00490-20. doi: 10.1128/mSphere.00490-20

TABLE 2.

MIC range and MIC50 in carbapenemase-producing Klebsiella pneumoniae

Drug MIC range (MIC50) (mg/liter)
IMP-1 producers IMP-6 producers
Meropenem 0.25 to 64 (1) 0.25 to 16 (1)
Imipenem 0.125 to 64 (1) ≤0.06 to 0.5 (0.125)
Piperacillin 4 to 256 (128) 8 to >256 (>256)
Tazobactam/piperacillin 2 to 256 (64) 0.5 to 32 (8)
Cefotaxime 16 to 128 (64) 8 to >256 (64)
Ceftazidime 128 to >256 (>256) 4 to >256 (32)
Cefmetazole 256 to >256 (>256) 8 to >256 (64)
Aztreonam ≤0.06 to 1 (0.25) ≤0.06 to 128 (8)
Levofloxacin ≤0.06 to 32 (16) ≤0.06 to 128 (16)
Gentamicin 0.25 to 4 (1) 0.5 to 32 (2)
Amikacin 0.25 to 2 (1) 0.5 to 8 (2)