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. Author manuscript; available in PMC: 2020 Oct 23.
Published in final edited form as: Histopathology. 2017 Dec 4;72(4):588–600. doi: 10.1111/his.13395

Figure 3:

Figure 3:

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (SDH case #6, 17 year old male). This oncocytic neoplasm demonstrated solid, nested and acinar architecture (A). The solid nests featured eosinophilic cells with focal cytoplasmic vacuoles but no well-developed cytoplasmic inclusions (B). In multiple areas, micropapillae projected into acinar lumens and surrounded basement membrane material, simulating the appearance of the t(6;11) renal cell carcinoma (C). The neoplasm demonstrated loss of succinate dehydrogenase B immunoreactivity. Note the intact labeling of the renal tubules and stroma at the left of the lesion (D).