Figure 4.

The schematic drawings (left and middle) of (a) the native form, (b) topological isomer, and (c) Acm₂-precursor peptide of ST_h(6–18). Their backbone structures were illustrated by cartoon representations. The orange spheres represent the Cα of Cys. The disulfide linkages, C1–C4, C2–C5, and C3–C6, were illustrated by stick representation colored by blue, red, and green, respectively. Schematic drawings of each structure (right) showed the right or the left-handed spiral of their backbone when seen from the N- to the C-terminal.