Table 2.
Variability of Chromosome Copy Number | Cell Number with Modified Chromosome Structure, % | ||||||
---|---|---|---|---|---|---|---|
Cells | Chromosome Variability | Modal Class | Breaks with Preservation of Genet Material | Deletions | Translocations | HSRs Presence | |
RJK | 16-23 | 17-19 | 0-2 | 16 | 22 | 11 | 0 |
RJK-PAA | 15-32 | Not evident | 0-5 | 11 | 50 | 17 | 0 |
RJKEB | 18-32 | 18 | 0-3 | 5 | 20 | 10 | 100 |
RJKEB-PAA | 15-21 | 18-20 | 0-3 | 33 | 55 | 0 | 100 |
Karyotype characterization of RJK, RJKEB, RJK-PAA, RJKEB-PAA cells. Abbreviations: RJK—Chinese hamster cells CHLV-79 RJK; RJKEB—RJK resistant to ethidium bromide; PAA—polyallylamine hydrochloride; RJK-PAA—RJK cells after PAA treatment; RJKEB-PAA—RJKEB cells after PAA treatment; EB—ethidium bromide; HSR—homogeneously stained region.