Table 3. Hazard ratios for rates of clearance of infection, by clone and by infection event.
| Predictors | Categories | Hazard ratio by clone (95% CI) | Hazard ratio by infection event (95% CI) | ||
|---|---|---|---|---|---|
| Unadjusted | Adjusted | Unadjusted | Adjusted | ||
| Sex | Male | ref | ref | ref | ref |
| Female | 1.92 (1.19–3.11) | 1.82 (1.20–2.75) | 2.30 (1.20–4.42) | 2.07 (1.24–3.47) | |
| Age | 16 years or greater | ref | ref | ref | ref |
| 5–15 years | 0.66 (0.39–1.10) | 0.81 (0.49–1.36) | 0.82 (0.39–1.74) | 1.27 (0.72–2.25) | |
| <5 years | 1.64 (0.79–3.41) | 1.55 (0.76–3.17) | 2.01 (0.80–5.00) | 1.75 (0.87–3.53) | |
| Complexity of infection (COI) | Polyclonal (COI > 1) | ref | -- | ref | -- |
| Monoclonal (COI = 1) | 1.63 (1.03–2.57) | -- | 0.95 (0.38–2.34) | -- | |
| Infection status | Present at baseline | ref | ref | ref | ref |
| New infection | 1.94 (1.22–3.07) | 1.75 (1.05–2.94) | 4.66 (2.58–8.42) | 4.32 (2.59–7.20) | |
| Parasite density * | 0.85 (0.69–1.06) | 0.81 (0.65–1.00) | 0.41 (0.32–0.51) | 0.44 (0.35–0.54) | |
*Increasing parasite density (log10) in parasites/microliter, as measured by qPCR.